降钙素原治疗肝硬化并发自发性细菌性腹膜炎的临床意义  

Clinical significance of procalcitonin in treating liver cirrhosis complicated with spontaneous bacterial peritonitis

作　　者：孟玉丽[1] 张红旭[1] 王斌[1] 

机构地区：[1]漯河医学高等专科学校第一附属医院肝病科,河南漯河462000

出　　处：《中国实用医刊》2015年第19期43-44,共2页Chinese Journal of Practical Medicine

摘　　要：目的：分析血清降钙素原（PCT）在肝硬化并发自发性细菌性腹膜炎（SBP）诊断和预后的应用价值。方法选择漯河医学高等专科学校第一附属医院2013年12月至2014年12月实施治疗的40例肝硬化腹水患者作为观察组，另外选取我院同期体检的40例健康人员作为对照组，对比分析两组血清 PCT。结果和对照组相比，伴 SBP 患者的血清 PCT 显著偏高，差异有统计学意义（P 〈0.05）；伴 SBP 患者的血清 PCT 水平也明显高于非伴SBP 患者，差异有统计学意义（P 〈0.05）；对照组和非伴 SBP 患者血清 PCT 差异未见统计学意义（P 〉0.05）。结论肝硬化并发 SBP 患者早期诊断和预后判断中，血清 PCT 检测具有重要应用价值。Objective To analyze the application value of serum procalcitonin （PCT） in treating liver cirrhosis com-plicated with spontaneous bacterial peritonitis （SBP）. Methods Forty cirrhotic patients with ascites from December 2013 to December 2014 were selected as observation group, 40 health person for physical examination were selected as control group, the serum PCT in two groups were compared and analyzed. Results In comparison with the control group, the level of serum PCT in patients with SBP was significantly higher （P 〈0. 05）; the level of serum PCT in patients with SBP was significantly higher than that in patients without SBP （P 〈 0. 05）; The difference of level of serum PCT in control group and patients without SBP had no significant difference（P 〉 0. 05）. Conclusions Serum PCT detection is a useful tool for the early diagnosis and prognosis of liver cirrhosis complicated with SBP.

关 键 词：肝硬化 自发性细菌性腹膜炎 降钙素原 

分 类 号：R575.2[医药卫生—消化系统]