深板层角膜移植治疗感染性角膜炎的临床观察  

Clinical Observation of Deep Lamellar Keratoplasty for the Treatment of Infectious Keratitis

作　　者：张键[1] 孙立新[1] 余德成[1] 胡昌波[1] 

机构地区：[1]常德市第一人民医院眼科,湖南常德415000

出　　处：《临床医学工程》2015年第9期1165-1166,共2页Clinical Medicine & Engineering

摘　　要：目的探讨深板层角膜移植治疗感染性角膜炎的临床疗效。方法将我院收治的80例感染性角膜炎患者随机分为两组,每组40例,观察组采取深板层角膜移植术治疗,对照组采取穿透性角膜移植术治疗,比较两组患者术后角膜内皮细胞数目变化及视力矫正情况。结果两组患者术后角膜内皮细胞数目均有不同程度下降,但对照组术后1个月、6个月、12个月、24个月角膜内皮细胞数目较同期观察组下降更明显(P<0.05);两组患者术后视力较术前均明显改善(P<0.01),但观察组改善更为明显(P<0.01)。结论深板层角膜移植治疗感染性角膜炎疗效显著,值得临床推广应用。Objective To explore the clinical efficacy of deep lamellar keratoplasty for treating infectious keratitis. Methods Eighty patients with infectious keratitis admitted to our hospital were randomly divided into two groups, with 40 cases in each group. The observation group was treated with deep lamellar keratoplasty, while the control group was treated with penetrating keratoplasty. The corneal endothelial cell number and visual acuity correction after therapy were compared between two groups. Results The corneal endothelial cell numbers of two groups after therapy decreased at different degrees, and the corneal endothelial cell numbers of control group 1, 6, 12 and 24 months after surgery were significantly lower than those of observation group at the same period （P〈0.05）. After surgery, both groups had improved vision （P〈0.01）, and the observation group was superior to the control group （P〈0.01）. Conclusions Deep lamellar keratoplasty has significant efficacy for the treatment of infectious keratitis, which is worthy of clinical promotion.

关 键 词：深板层角膜移植 感染性角膜炎 疗效 

分 类 号：R772.21[医药卫生—眼科] R779.65[医药卫生—临床医学]