无抽搐电休克治疗对精神分裂症患者记忆的远期影响  

The long-term effect of MECT on memory in patients with schizophrenia

作　　者：杨楹[1] 

机构地区：[1]山东省精神卫生中心,山东济南250014

出　　处：《精神医学杂志》2015年第4期278-280,共3页Journal of Psychiatry

摘　　要：目的探讨无抽搐电休克治疗(MECT)对精神分裂症患者记忆的远期影响。方法选取至少6个月前接受过MECT的精神分裂症患者40例为MECT组,从未接受过MECT的精神分裂症患者40例为非MECT组,健康人群40例为对照组,采用自编的主观记忆评估问卷、认知功能成套测验(MCCB)及词汇记忆测验视觉版(WMT)进行评估。结果MECT组和非MECT组PANSS评分高于对照组(P<0.05),GAF评分低于对照组(P<0.05);MECT组和非MECT组数字序列、空间广度、言语记忆、视觉记忆、即时再认、延迟再认、一致性、主观记忆评估评分均低于对照组(P<0.05),除视觉记忆得分外,MECT组上述各项评分低于非MECT组(P<0.05)。结论 MECT可能对精神分裂症患者的记忆功能有远期影响。Objective To explore the long-term impact of Modified Electric Convulsive Therapy （ MECT ） on memory in patientwithschizophrenia.Methods 40schizophrenicpatientswhohadbeentreatedwithMECTatleast6monthsago（MECT group）, 40 schizoprenic patients never treated with MECT （non-MECT group） and 40 healthy controls （control group） were assessed with self-designed subjective memory questionnaire, Matrics Consensus Cognitive Battery （ MCCB） and Word Memory Test （ WMT） .Results Compared with control group, MECT group and non-MECT group showed significantly higher score of PANSS （P〈0.05） and significantly lower score of GAF （P〈0.05）.Scores of digit sequence, spatial span, verbal memory, visual memory, instant recognition, delayed recognition, consistency, subjective memory assessment in MECT group and non-MECT group were significantly lower than those in control group （P〈0.05）.Scores of all above-mentioned tests except visual memory in MECT group were significantly lower than those in non-MECT group （P〈0.05）.Conclusion MECT may has long-term negative effect on the mnemonic function in patients with schizophrenia.

关 键 词：无抽搐电休克治疗 精神分裂症 记忆 远期影响 

分 类 号：R749.3[医药卫生—神经病学与精神病学]