脑细胞胶质瘤的多模态影像学表现及鉴别诊断  

Multimodal imaging findings and differential diagnosis of ganglioglioma

作　　者：刘学兵[1] 陈自谦[2] 许尚文[2] 刘乐[1] 

机构地区：[1]蚌埠医学院医学影像系,安徽蚌埠233030 [2]南京军区福州总医院医学影像学中心,福建福州350025

出　　处：《医学影像学杂志》2015年第9期1533-1536,共4页Journal of Medical Imaging

摘　　要：目的探讨颅内神经节细胞胶质瘤的多种影像学表现。方法回顾性分析经免疫组化证实的24例节细胞胶质瘤的多种影像学表现。结果 24例病灶均为单发,21例位于幕上,其中9例位于颞叶,7例位于额叶,额颞叶2例,额顶叶、丘脑及顶叶各1例。3例位于幕下,脑干、四脑室及延髓各1例。囊实性21例,实性2例,囊性1例。增强后囊性成分未见强化,囊壁及实性成分不强化或轻中度强化。MRS示实性部分Cho/Cr及NAA/Cr降低,Cho/NAA升高。7例患者行CT或PET-CT检查,病灶表现为等低密度,5例出现明显钙化灶。4例PET-CT上表现为低代谢。结论节细胞胶质瘤影像学表现多样,但仍具有一定特征性,结合多种影像学技术可以提高诊断。Objective To evaluate the multimodal imaging findings of intracranial ganglioglioma. Methods Medical ima- ging findings in twenty-four with intracranial gangliogliomas confirmed by pathology were analyzed retrospectively. Results All cases were solitary. 21 cases were supratentorial area, including the temporal lobe （9 cases）, the frontal lobe （7 ca- ses）, the frontal-temporal lobe （2 cases）, the thalamus and the pa-rietal lobe respectively （1 multipe-lesion case）. 3 cases were subtentorial area, including brainstem, fourth ventricle and me-dulla oblongata. The cystic-solid tumors were ob- served in 21 patients, the solid lesion was observed in 1 patient and the cystic mass was observed in 2 patients. Non- rein- forcement could be seen in cystic compoments. Non-reinforcement or Mild-to-moderate reinforcement could be seen in solid compoments. The solid components showed a reduced Cho/Cr and NAA/Cr ratio and an increased Cho/NAA ratio in MRS. In 3 cases with CT and 4 cases with PETCT plain scan, calcification was seen in 5 cases. 4 case showed poor me- tabolizers in PET-CT. Conclusion Although the medical imaging appearances of gang-lioglioma are diversity, intracranial gangliogliomas still have certain character-istie imaging features, which is helpful for the diagnosis pre-operatively with a variety of imaging techniques.

关 键 词：节细胞胶质瘤 多模态影像学表现 

分 类 号：R742[医药卫生—神经病学与精神病学] R445[医药卫生—临床医学]