骨上皮样血管内皮瘤2例并文献复习  

Epithelioid hemangioendothelioma of bone: Report of 2 cases and review of literature

作　　者：曲文书 华海清 杨宁蓉 

机构地区：[1]解放军八一医院全军肿瘤中心肿瘤内科,江苏南京210002

出　　处：《现代肿瘤医学》2015年第20期3024-3026,共3页Journal of Modern Oncology

摘　　要：目的:探讨2例骨上皮样血管内皮瘤(epithelioid hemangioendothelioma,EHE)的临床特点、治疗措施和预后因素。方法:回顾性分析2例原发于骨的EHE临床资料、诊断、治疗以及随访情况,并结合文献进行讨论。结果:2例骨EHE中男性和女性各1例,低度恶性的单发骨EHE患者经过局部病灶的放疗、TE方案联合恩度等综合治疗,目前仍存活;侵袭性多发病灶的骨EHE患者经过TE方案联合恩度系统治疗、局部TOMO等综合治疗,病情进展后死亡。结论:骨EHE的预后主要取决于肿瘤组织学级别和发生的部位;综合治疗可适当延长生存期,规范治疗尚无循证医学依据。Objective:To investigate the clinicopathological characteristics,treatment and prognostic factor of the epithelioid hemangioendothelioma(EHE)derived from bone.Methods:Two cases of EHE in bone were retrospective-ly reviewed.Results:There were 1male and 1 female in the two cases.One case with low aggressive solitary EHE of the bone after radiotherapy,still alive.Another case with aggressive multifocal EHE of the bone after TE regimen com-bined with Endostar system treatment,TOMO radiotherapy and other comprehensive treatment,died after disease pro-gression.Conclusion:The prognosis of EHE derived from bone depends mainly on the tumor histological grade and site of occurrence.Comprehensive treatment can be appropriately extended survival time.There is no evidence -based medicine on specification of the treatment.

关 键 词：骨肿瘤 上皮样血管内皮瘤 治疗 

分 类 号：R738.1[医药卫生—肿瘤]