抗精神病药物所致ST-T改变的心电图特征分析  

ANALYSIS OF CHARACTERISTICS OF ST-T CHANGES OF ELECTROCARDIOGRAM CAUSED BY ANTIPSYCHOTIC DRUGS

作　　者：钟智勇 冯艳萍 李忠超 刘波 

机构地区：[1]四川省自贡精神卫生中心,643020

出　　处：《现代电生理学杂志》2015年第3期140-143,共4页Journal of Modern Electrophysiology

摘　　要：目的:探讨抗精神病药物所致心电图非特异性ST-T异常的心电图特征。方法:选择服用抗精神病药物所致心电图改变患者73例,以慢性冠状动脉供血不足患者58例为对照组。两组对照分析心电图ST-T改变的异同点。结果:两组比较:ST段时间,ST段下移程度,ST段下移形态,是否伴发T波改变,发生ST-T改变导联分布等,差异均有统计学意义(P<0.05或0.01)。结论:服抗精神病药物所致非特异ST-T改变与原发性ST-T改变心电图表现不同,其特征为:ST段时间不延长、ST段下移幅度不大、以水平型下移为主、多数不伴发T波改变、多发生在II、lII、aVF导联(下壁)。Objective： To explore the characteristics of nonspecific abnormal ST-T of electrocardiogram （ ECG ） caused by antipsychotic drugs. Methods： 73 cases with nonspecific abnormal ST-T caused by antipsychotic drugs were as the study group, 58 cases with chronic coronary insufficiency as control group. Results： Contrast analysis between the two groups： ST-segment time, the degree of ST-segment depression, the shape of ST-segment depression, whether T wave change or not, distribution of ST-T change lead etc, all of them had significant differences （P 〈 0.05 or 0.01 ） . Conclusion： ECG manifestations between the nonspecific ST-T changes caused by antipsychotic drugs and the primary ST-T changes have differences, and has the following characteristics： no ST-segment time prolongation, mild ST-segment depression, most with the horizontal depression of ST-segment, most without T wave change, most occur on II, lII and aVF leads （ inferior wall ） .

关 键 词：ST-T改变 抗精神病药物 慢性冠状动脉供血不足 

分 类 号：R749[医药卫生—神经病学与精神病学] R540.41[医药卫生—临床医学]