骶骨肿瘤切除术后切口感染的危险因素分析  

Analysis of risk factors of incision infection after sacral tumor resection

作　　者：李凯[1] 

机构地区：[1]宝鸡市中心医院骨科,陕西宝鸡721008

出　　处：《中国医学前沿杂志（电子版）》2015年第8期71-74,共4页Chinese Journal of the Frontiers of Medical Science(Electronic Version)

摘　　要：目的探究骶骨肿瘤切除术后切口感染的危险因素,为临床预防感染提供参考。方法回顾分析2009年1月至2013年2月本院收治的59例骶骨肿瘤切除术患者切口感染的预防及诊断经验,应用单变量Logistic回归分析切口感染的相关危险因素,对筛选出的因素进行多因素Logistic分析。结果 59例患者中感染15例,4例为浅表感染,11例为深部感染;15例中12例细菌培养阳性,其中3例为混合细菌感染。单因素分析显示,手术区曾接受放疗、手术次数、手术时间、切口距肛门距离、糖尿病病史、肿瘤最大直径>10 cm、术中术后直肠破裂、应用内固定物、术后脑脊液漏与切口感染的发生呈正相关(P<0.05),其余因素与切口感染无明显相关性(P>0.05)。Logistic分析结果提示,手术区曾接受放疗、应用内固定物、术中术后直肠破裂、手术时间、糖尿病病史、术后脑脊液漏是导致术后切口感染的独立危险因素。结论在对骶骨肿瘤患者实施手术治疗时,应避免或减轻以上独立危险因素,减少患者切口感染风险。Objective To explore the risk factors of incision infection after sacral tumor resection for providing references to clinical infection prevention. Method Prevention and diagnosis experiences of 59 cases of patients with sacral tumor resection in our hospital from January 2009 to February 2013 were retrospectively analyzed. Univariate Logistic regression analysis was used to analyze associated risk factors of incision infection. Multivariate Logistic analysis was used to analyze the screened factors. Result Among the 59 cases, 15 cases were infected, 4 cases of superficial infection, 11 cases of deep infection, 12 cases of bacterial culture positive, 3 cases were mixed bacterial infection. Univariate analysis showed that existed radiotherapy in surgical area, operation frequency, operation time, the distance of incision to the anus, history of diabetes, maximum tumor diameter > 10 cm, intraoperative and postoperative rectal rupture, application of internal fixation, postoperative cerebrospinal fluid leakage had significant positive correlation with incision infection. The other factors had no significant correlation with incision infection(P > 0.05). Logistic analysis result indicated that the existed radiotherapy in surgical area, application of internal fixation, intraoperative and postoperative rectal rupture, operation time, history of diabetes, postoperative cerebrospinal fluid leakage were independent risk factors for incision infection. Conclusion When operating on patients with sacral tumor, the above independent risk factors that could cause incision infection should be avoided to reduce the risk of infection.

关 键 词：骶骨肿瘤切除术 切口感染 危险因素 LOGISTIC分析 

分 类 号：R738.1[医药卫生—肿瘤]