卵巢肿瘤患者血清胱抑素C表达水平及临床意义  

Variance of serum cystatin C levels in patients with ovarian cancer and its significance

作　　者：郑淑华[1] 黄瑞玉[1] 穆小萍[1] 卢春敏[1] 

机构地区：[1]广东省妇幼保健院检验科,广东广州511400

出　　处：《海南医学》2015年第17期2551-2553,共3页Hainan Medical Journal

摘　　要：目的检测卵巢肿瘤患者血清胱抑素C的表达水平,分析其发生变化的原因及临床意义。方法收集40例卵巢癌患者、40例卵巢良性肿瘤患者和40例健康体检妇女的血清标本,采用乳胶增强免疫透射比浊法分别对标本进行血清胱抑素C的检测,总体均值比较采用单因素方差分析,组间均值两两比较采用LSD分析。结果卵巢癌患者血清胱抑素C水平均比卵巢良性肿瘤患者和健康体检妇女的血清水平显著升高,差异均有显著统计学意义(P<0.01),而卵巢良性肿瘤者与健康体检者比较则差异无统计学意义(P>0.05)。结论卵巢癌患者血清胱抑素C水平显著升高,提示胱抑素C参与了卵巢癌的发生发展及转归的过程。Objective To determine the levels of cystatin C in patients with ovarian cancer, and to analyze the reason of variance and its significance. Methods Forty ovarian cancer patients, 40 ovarian benign tumor patients, and 40 healthy individuals were included in the study. Serum cystatin C was detected by the method of Emulsion Enhanced Turbi-dimetric Immuno-Assay. All data were statistically analyzed using the One-Way ANOVA and LSD method. Results The levels of cystatin C in ovarian cancer group were significantly higher than those in both ovarian benign tumor group and healthy group （P〈0.01）. And there was no statistically significant difference between data of the ovarian benign tumor group and healthy group （P〉0.05）. Conclusion The significant increase of cystatin C level in patients with ovarian cancer indicates that cystatin C is actually involved in the development of ovarian cancer.

关 键 词：卵巢肿瘤 侵袭 胱抑素C 

分 类 号：R737.31[医药卫生—肿瘤]