银杏叶提取物与氯氮平治疗迟发性运动障碍的临床效果对比  

Clinical comparative study of the effect of Ginkgo biloba extract and clozapine in the treatment of tardive dyskinesia

作　　者：黄秀芳[1] 冯芳[1] 高晓奇[1] 李克松[1] 石秀华[1] 

机构地区：[1]河北省荣军医院,071000

出　　处：《神经疾病与精神卫生》2015年第4期389-390,共2页Journal of Neuroscience and Mental Health

摘　　要：目的：对比分析银杏叶提取物与氯氮平治疗迟发性运动障碍的临床效果。方法选取2013年1月1日～2015年1月1日纳入的60例迟发性运动障碍患者，分为对照组和实验组，各30例。给予对照组患者氯氮平治疗，给予实验组患者银杏叶提取物治疗，观察、比较两组患者的治疗结果。结果实验组的治疗后第4，8，12周末的AIMS总分均高于对照组，且差异有统计学意义（P＜0．05）；治疗后第8，12周末实验组的TESS总分显著下降，与对照组比较差异有统计学意义（P＜0．05）。结论银杏叶提取物较氯氮平治疗迟发性运动障碍具有更好疗效和改善指标，可考虑在临床中加以推广应用。Objective To compare and analyze the clinical effect of Ginkgo biloba extract and clozapine on treating tardive dyskinesia .Methods Sixty tardive dyskinesia patients from January 1 ,2013 to January 1 , 2015 of our hospital were selected ,and divided into control and test group ,each of 30 cases .Clozapine treat‐ment administered to the control group of patients ,given the test group patients Ginkgo biloba extract . Curative effect was observed and compared between the two groups .Results AIMS scores in test group after 4 ,8 ,12 weeks of treatment were higher than that of control group ,and the differences were statisti‐cally significant （P〈 0 .05）;Compared with the control group ,the TESS scores in test group decreased obviously ,the differences were statistically significant （P 〈 0 .05） .Conclusions Ginkgo biloba extract than clozapine in the treatment of tardive dyskinesia has better efficacy ,and may be considered for appli‐cation in clinical .

关 键 词：银杏叶提取物 氯氮平 迟发性运动障碍 临床效果 对比研究 

分 类 号：R749.61[医药卫生—神经病学与精神病学]