Analysis and Treatment of Multiple Severe Venous Vascular Malformation Syndrome Combined with Coagulopathy  

作　　者：Jun-Bo Qiao Jin Li Xie-Fu Zhang 

机构地区：[1]Department of Hemangioma Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou University People's Hospital (Henan Provincial People's Hospital), Zhengzhou, Henan 450052, China [2]Department of Ophthalmology, 7hengzhou University People's Hospital (Henan Provincial People's Hospital), Henan Eye Institute and Henan Eye Hospital Zhengzhou, Henan 450052, China [3]Department of General Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China

出　　处：《Chinese Medical Journal》2015年第18期2546-2548,共3页中华医学杂志（英文版）

摘　　要：According to a new international classification of vascular lesions, venous vascular malformation has become the most common type of congenital vascular malformation. A characteristic of this disease is its life-long progressive development, which is the main cause of harm to health and is different from hemangioma. Severe hemangioma with thrombocytopenia （Kasabach-Merritt syndrome） is often encountered in children, especially in infants younger than 1 year old. Coagulation abnormalities in Kasabach-Merritt syndrome are mainly caused by increased platelet destruction. Whereas, severe venous malformation-associated coagulopathy is attributed to the depletion of coagulation substances and extensive intravenous coagulation, and it occurs in adults. In principle, surgery is required.According to a new international classification of vascular lesions, venous vascular malformation has become the most common type of congenital vascular malformation. A characteristic of this disease is its life-long progressive development, which is the main cause of harm to health and is different from hemangioma. Severe hemangioma with thrombocytopenia （Kasabach-Merritt syndrome） is often encountered in children, especially in infants younger than 1 year old. Coagulation abnormalities in Kasabach-Merritt syndrome are mainly caused by increased platelet destruction. Whereas, severe venous malformation-associated coagulopathy is attributed to the depletion of coagulation substances and extensive intravenous coagulation, and it occurs in adults. In principle, surgery is required.

关 键 词：COAGULOPATHY Treatment Venous Vascular Malformation 

分 类 号：Q592.1[生物学—生物化学] TB559[理学—物理]