supported by National Natural Science Foundation of China(81571916);Key Research and Development(R&D)Program of Zhejiang Province(2024C03186);Major Project of National-Zhejiang Provincial Administration of Traditional Chinese Medicine(GZY-ZJ-KJ-24030).
BACKGROUND:Trauma-induced coagulopathy(TIC)due to serious injuries significantly leads to increased mortality and morbidity among elderly patients.However,the risk factors of TIC are not well elucidated.This study aim...
National Natural Science Foundation of China(No.32171342;51772100);National Key Research and Development Program of China(2022YFB3804300).
Hemostatic materials are essential for managing acute bleeding in medical settings.Chitosan(CS)shows promise in hemostasis but its underlying mechanism remains incompletely understood.We unexpectedly discovered that c...
Acute fatty liver of pregnancy (AFLP) is a rare obstetric complication, and despite improvements in recognition and management over recent decades, it still carries a high risk of maternal and fetal morbidity and mort...
Corisin,a 19 amino acid proapoptotic peptide derived from the lung microbiota(i.e.,by Staphylococci),is implicated in the pathogenesis of acute lung injury and exacerbation of pulmonary fibrosis.Recent evidence also s...
Hematological abnormalities are common in cirrhosis and are associated with various pathophysiological mechanisms.Studies have documented a prevalence of thrombocytopenia,leukopenia,and anemia in patients with compens...
Yunnan Fundamental Research Projects(202201AU070167,202301AT070258);Yunnan Key Laboratory of Formulated Granules(202105AG070014).
In this review,the databases searched were PubMed and Web of Science.It is believed that the main causes of acute lung injury(ALI)and acute respiratory distress syndrome(ARDS)are inflammatory response disorders,excess...
supported by the National Key Research and Development Program of China(2021YFC2501800);Shanghai Committee of Science and Technology(20Y11900100,21MC1930400,and 20DZ2261200);Clinical Research Plan of Shanghai Hospital Development Center(SHDC2020CR4059)。
BACKGROUND:Disseminated intravascular coagulation(DIC)is associated with increased mortality in sepsis patients.In this study,we aimed to assess the clinical ability of sepsis-induced coagulopathy(SIC)and sepsis-assoc...
funded by Chinese Medicine Education Association(No.2022KTz013).
Purpose:In patients with heatstroke, disseminated intravascular coagulation (DIC) is associated with greater risk of in-hospital mortality. However, time-consuming assays or a complex diagnostic system may delay immed...
The Sepsis Coagulopathy Asahi Recombinant LE Thrombomodulin(SCARLET)trial has many defects,and thus cannot be the terminator of recombinant thrombomodulin(rTM).On the contrary,it provides sufficient evidence for furth...
Dear Editor,The severe coagulation syndrome in numerous organs is the major life-threatening conditions characterizing the acute infection by SARS-CoV-2.Endothelial inflammation/dysfunction,platelet hyper-reactivity,g...