Acute Fatty Liver of Pregnancy—A Case Report in Grange University Hospital, Wales  

作　　者：Madinah Azeez Alice Tayler Simran Sharma Madinah Azeez;Alice Tayler;Simran Sharma(Grange University Hospital, Cwmbran, Wales, UK)

机构地区：[1]Grange University Hospital, Cwmbran, Wales, UK

出　　处：《Open Journal of Obstetrics and Gynecology》2024年第10期1577-1582,共6页妇产科期刊（英文）

摘　　要：Acute fatty liver of pregnancy (AFLP) is a rare obstetric complication, and despite improvements in recognition and management over recent decades, it still carries a high risk of maternal and fetal morbidity and mortality. Patients typically present in the third trimester with non-specific symptoms, including nausea and vomiting, upper abdominal pain, malaise and anorexia. Initial diagnosis can be challenging due to the sometimes-insidious presentation, as well as the difficulty in distinguishing between AFLP and other conditions seen in pregnancy with overlapping features. We report a case study of a 32-year-old primigravida who presented with mild and non-specific symptoms, and examination findings leading to a timely diagnosis of AFLP were made. This case highlights the importance of early recognition, prompt intervention, and multidisciplinary management to achieve optimal maternal and fetal outcomes.Acute fatty liver of pregnancy (AFLP) is a rare obstetric complication, and despite improvements in recognition and management over recent decades, it still carries a high risk of maternal and fetal morbidity and mortality. Patients typically present in the third trimester with non-specific symptoms, including nausea and vomiting, upper abdominal pain, malaise and anorexia. Initial diagnosis can be challenging due to the sometimes-insidious presentation, as well as the difficulty in distinguishing between AFLP and other conditions seen in pregnancy with overlapping features. We report a case study of a 32-year-old primigravida who presented with mild and non-specific symptoms, and examination findings leading to a timely diagnosis of AFLP were made. This case highlights the importance of early recognition, prompt intervention, and multidisciplinary management to achieve optimal maternal and fetal outcomes.

关 键 词：Liver Disease COAGULOPATHY Obstetrics Medicine 

分 类 号：R71[医药卫生—妇产科学]