TACE联合立体定向放疗对肝癌伴门静脉癌栓患者预后的影响  

Effect of TACE Combined with Stereotactic Radiotherapy on the Prognosis of Hepatocellular Carcinoma with Portal Vein Thrombosis Prognostic

作　　者：朱中山[1] 严文辉[1] 彭新茂[1] 李小兵[1] 杨洲[1] 

机构地区：[1]湖南省第二人民医院肿瘤科,410007

出　　处：《实用癌症杂志》2014年第6期681-683,共3页The Practical Journal of Cancer

摘　　要：目的探讨TACE联合立体定向放疗治疗肝癌伴门静脉癌栓的患者生存率及不良反应。方法选取84例肝癌伴门静脉癌栓患者作为研究对象。随机分为治疗组和对照组,各42例。治疗组采用TACE联合立体定向放疗,对照组仅采用TACE治疗。结果治疗组和对照组经治疗后12个月和18个月的生存率分别为83.34%、42.92%和57.14%、23.83%,差异具有统计学意义(P<0.05和P<0.01),而2组治疗后6个月的生存率及不良反应发生率无明显差异。结论 TACE联合立体定向放疗延长了肝癌伴门静脉癌栓患者的生存期,提高了患者的生活质量,改善了预后。Objective To investigate the survival rate and adverse reactions of TACE and stereotactic radiotherapy for hepatocellular carcinoma with portal vein thrombosis. Methods 84 cases of hepatocellular carcinoma with portal vein thrombosis patients were selected as research subjects. The patients were randomly divided into the treatment group and the control group,each group contain 42 cases. The treatment group were treated with TACE and stereotactic radiotherapy; and the control group received only TACE treatment. Results Survival rates of the treatment group and the control group 12 months and 18 months after treatment were 83. 34%,42. 92% and 57. 14%,23. 83%,and the difference was significant( P < 0. 05 and P < 0. 01),while survival rates and the incidence of adverse reactions of the 2 groups 6 months after treatment had no significant difference. Conclusion TACE combined with stereotactic radiotherapy for hepatocellular carcinoma with portal vein thrombosis prolongs survival,improves quality of life and prognosis of the patients.

关 键 词：TACE 立体定向 放疗 肝癌伴门静脉癌栓 

分 类 号：R735.7[医药卫生—肿瘤]