视网膜中央静脉阻塞患者血浆TXB_2、6-K-PGF_(1α)改变与气血辨证的关系研究  

Study of the Relationship between Changes of Plasma thromboxane B_2(TXB_2),6-K-PGF_(1α) and Differentiation of Syndromes of Qi and Blood in Patients with Central Retinal Vein Occlusion

作　　者：任大元[1] 荣亮[1] 卢丙辰[2] 

机构地区：[1]解放军148医院眼科,山东淄博255300 [2]河南省中医院眼科,河南郑州450008

出　　处：《山东中医药大学学报》2015年第5期427-428,共2页Journal of Shandong University of Traditional Chinese Medicine

摘　　要：目的 :探讨视网膜中央静脉阻塞(CRVO)患者血浆血栓素B2(TXB2)、6-酮-前列腺素F1α(6-K-PGF1α)改变与气血辨证的内在关系。方法:108例患者采用气血辨证分为气虚血瘀组55例,气滞血瘀组53例,正常对照组50例为自愿体检者,观察比较三组患者的血浆TXB2、6-K-PGF1α水平。结果:CRVO患者血浆TXB2、6-K-PGF1α水平及T/K值明显高于正常对照组(P<0.01),气虚血瘀组与气滞血瘀组比较无显著性差异(P>0.05)。结论:瘀血为CRVO患者致盲的首要因素,治疗应以活血化瘀为主。Objective：To explore the internal relation between the changes of plasma thromboxane B2（TXB2）, F1α（6-K-PGF1α） and the differentiation of syndromes of qi and blood in patients with central retinal vein occlusion （CRVO）. Methods：Syndrome differentiation of qi and blood was made on 108 cases of CRVO. There were 55 cases of qi deficiency and blood stasis syndrome and 53 cases of qi stagnation and blood stasis syndrome. 50 cases in the control group were volunteers for physical examination. The levels of TXB2 and 6-K-PGF1α of them were observed. Results：The levels of TXB2 and 6-K-PGF1α of patients with CRVO were much higher than those of the normal control group（P〈0.01）. No significant difference（P〉0.05） was found in the comparison between syndrome of blood stagnancy due to qi deficiency and syndrome of blood stagnancy due to qi stagnancy. Conclusion：Blood stasis is the first critical factor which leads to blindness , so the treatment should be based on promoting blood circulation and removing blood stasis.

关 键 词：视网膜中央静脉阻塞 血栓素B2 6-酮-前列腺素F1Α 气血辨证 THROMBOXANE B2 6-K-PGF1Α 

分 类 号：R276.74[医药卫生—中医五官科学]