THROMBOXANE

作品数:60被引量:99H指数:6
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相关领域:医药卫生更多>>
相关作者:王思琪陈晰李运曼王志华薛娜更多>>
相关机构:南京医科大学中国药科大学第三军医大学西南医院北京医科大学更多>>
相关期刊:《Chinese Journal of Traumatology》《Cellular & Molecular Immunology》《现代生物医学进展》《Chinese Journal of Integrative Medicine》更多>>
相关基金:国家科技重大专项国家自然科学基金陕西省自然科学基金瑞士科学基金更多>>
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Increased susceptibility of aging gastric mucosa to injury and delayed healing:Clinical implications被引量:9
《World Journal of Gastroenterology》2018年第42期4721-4727,共7页Andrzej S Tarnawski Amrita Ahluwalia 
Merit Review Award from the United States Department of Veterans Affairs Biomedical Laboratory Research and Development Service,No.I01 BX000626-05A2 to Tarnawski AS
In this editorial we comment on the article by Fukushi K et al published in the recent issue of the World Journal of Gastroenterology 2018; 24(34): 3908-3918. We focus specifically on the mechanisms of the anti-thromb...
关键词:AGING gastric MUCOSA INJURY Low dose aspirin Platelets CYCLOOXYGENASE-1 CYCLOOXYGENASE-2 THROMBOXANE A-2 
Associations between thromboxane A synthase 1 gene polymorphisms and the risk of ischemic stroke in a Chinese Han population被引量:6
《Neural Regeneration Research》2018年第3期463-469,共7页Lei Li Zhi-yi He Yan-zhe Wang Xu Liu Li-ying Yuan 
supported by a grant from the National Natural Science Foundation of China,No.81070913
Thromboxane A synthase 1 (TBXAS1) catalyses the synthesis of thromboxane A2 (TXA2), which plays an important role in the pathogenesis of ischemic stroke. Thus, the TBXAS1 gene was investigated as a candidate gene ...
关键词:nerve regeneration brain injury ischemic stroke thromboxane A synthase 1 single nucleotide polymorphism case-control study thromboxane A2 Chinese Han population HAPLOTYPE large-artery atherosclerosis small-artery occlusion neural regeneration 
不同剂量羟考酮对腹腔镜胆囊切除术患者血清血栓素A2、血浆内皮素水平和免疫功能的影响被引量:3
《现代生物医学进展》2017年第25期4864-4868,共5页吴丽 薛娜 吴献伟 赵欣 王志华 
陕西省自然科学基金项目(20131037)
目的:探讨不同剂量羟考酮对腹腔镜胆囊切除术患者血清血栓素A2(TXA2)、血浆内皮素(ET)水平和免疫功能的影响。方法:选择2013年8月至2016年8月我院接诊的90例择期行腹腔镜胆囊切除术患者,以随机数表法分为3组,各30例。于手术开始前,均静...
关键词:腹腔镜胆囊切除术 羟考酮 血栓素A2 血浆内皮素 免疫功能 THROMBOXANE A2 
Endothelial overexpression of endothelin-1 modulates aortic, carotid, iliac and renal arterial responses in obese mice被引量:2
《Acta Pharmacologica Sinica》2017年第4期498-512,共15页Oliver BARETELLA Sookja K CHUNG Aimin XU Paul M VANHOUTFE 
This work was supported by the Swiss National Science Foundation (grants 138 754 and 143 672 to Oliver BARETELLA) and the Hong Kong Research Grant Council (780410M).
Endothelin-1 (ET-1) is essential for mammalian development and life, but it has also been implicated in increased cardiovascular risk under pathophysiological conditions. The aim of this study was to determine the i...
关键词:ENDOTHELIN-1 renal arteries contraction relaxation thromboxane prostanoid receptors serotonin acetylcholine ISOPROTERENOL CYCLOOXYGENASE endothelium-derived contracting factors PROSTACYCLIN obesity 
视网膜中央静脉阻塞患者血浆TXB_2、6-K-PGF_(1α)改变与气血辨证的关系研究
《山东中医药大学学报》2015年第5期427-428,共2页任大元 荣亮 卢丙辰 
目的 :探讨视网膜中央静脉阻塞(CRVO)患者血浆血栓素B2(TXB2)、6-酮-前列腺素F1α(6-K-PGF1α)改变与气血辨证的内在关系。方法:108例患者采用气血辨证分为气虚血瘀组55例,气滞血瘀组53例,正常对照组50例为自愿体检者,观察比较三组患者...
关键词:视网膜中央静脉阻塞 血栓素B2 6-酮-前列腺素F1Α 气血辨证 THROMBOXANE B2 6-K-PGF1Α 
缺血性脑卒中后血栓素A2的作用及相关药物研究进展被引量:14
《中国心血管病研究》2015年第2期117-120,共4页陈晰 王思琪 李运曼 
心脑血管疾病是全球发病率较高的一类疾病,其中脑卒中是全球引起死亡的第二大病因,也是致残的主要原因[1].据美国心脏协会报道,在美国,每19个死亡案例中就有1人死于脑卒中,平均每40秒就有1人患脑卒中[2].在所有脑卒中患者中,高达87%的...
关键词:血栓素A2 缺血性脑卒中 血小板 THROMBOXANE A2 
Changes in Plasma Levels of Vasoactive Factors in Patients Undergoing Abdominal Surgery
《Surgical Science》2014年第9期389-396,共8页Jinwen Zhang Meng Li Feng Zhang 
Background: To investigate the changes in plasma levels of endothelin (ET), nitric oxide (NO), prostacyclin (PGI2) and thromboxane A2 (TXA2) in patients undergoing abdominal operation. Materials and Methods: Thirty ca...
关键词:PROSTACYCLIN ENDOTHELIN THROMBOXANE A2 NITRIC Oxide Deep VENOUS Thrombosis THROMBOTIC State 
高浓度胰岛素对阿司匹林抑制的血小板中TXB2合成影响的研究被引量:1
《浙江临床医学》2014年第6期853-855,共3页高玉龙 龙炫辉 田平阁 高德禄 
全军十一五计划科技攻关基金资助项目(09BAk61801)
目的:探讨高浓度胰岛素是否影响阿司匹林抑制的血小板中TXB2合成。方法将制备的两组等体积的富含血小板血浆(PRP)分别加入浓度为30μU/ml和300μU/ml的胰岛素,37℃的环境下孵育3min,再次将上述两组的PRP分成等体积,分别用浓度为0...
关键词:胰岛素 阿司匹林 血小板 血小板聚集率 血栓烷B2 THROMBOXANE B2 
Platelet thromboxane(11-dehydro-Thromboxane B_2) and aspirin response in patients with diabetes and coronary artery disease被引量:13
《World Journal of Diabetes》2014年第2期115-127,共13页Luis R Lopez Kirk E Guyer Ignacio Garcia De La Torre Kelly R Pitts Eiji Matsuura Paul RJ Ames 
Supported by In part by the Senit Foundation,Scotland(United Kingdom);grant-in-aid for Scientific Research from the Ministry of Education,Culture,Sports,Science and Technology(Japan)
Aspirin(ASA) irreversibly inhibits platelet cyclooxygenase-1(COX-1) leading to decreased thromboxane-mediated platelet activation. The effect of ASA ingestion on thromboxane generation was evaluated in patients with d...
关键词:DIABETES Cardiovascular disease PLATELETS THROMBOXANE ASPIRIN 
Effect of polymorphism and type II diabetes on aspirin resistance in patients with unstable coronary artery disease被引量:8
《Chinese Medical Journal》2011年第11期1731-1734,共4页GAO Fei WANG Zan-xin MEN Jian-long REN Jing WEI Min-xin 
Background Aspirin is widely used in the secondary prevention of coronary artery diseases, including myocardial infarction, stroke, and vascular related deaths. However, the antiplatelet effect of aspirin appears to b...
关键词:aspirin  platelet aggregation  thromboxane genetic polymorphism 
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