PLATELETS

作品数:204被引量:582H指数:13
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相关领域:医药卫生更多>>
相关作者:李柏岩李文汉顾振纶阮长耿梁念慈更多>>
相关机构:哈尔滨医科大学苏州大学广东医学院湖南医科大学更多>>
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相关基金:国家自然科学基金北京市自然科学基金中国博士后科学基金安徽省自然科学基金更多>>
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Platelets indices clinical implications in diabetes mellitus:A broader insight
《World Journal of Diabetes》2025年第4期297-303,共7页Hyder Osman Mirghani 
Platelet indices(PIs)including high mean platelet volume(MPV),plateletcrit(PLC),and platelet distribution width(PLDW)are associated with poor glycemic control.In addition,they can indicate prothrombotic and procoagula...
关键词:Platelets indices Mean platelets volume Glucoregulation Cardiovascular risk 
Platelet activation relieves liver portal hypertension via the lymphatic system though the classical vascular endothelial growth factor receptor 3 signaling pathway
《World Journal of Gastroenterology》2025年第10期86-102,共17页Min Chen Jin-Bo Zhao Guang-Bo Wu Zheng-Hao Wu Gu-Qing Luo Zhi-Feng Zhao Chi-Hao Zhang Jia-Yun Lin Hong-Jie Li Xiao-Liang Qi Hai-Zhong Huo Abudukadier Tuersun Qiang Fan Lei Zheng Meng Luo 
Supported by the National Natural Science Foundation of China,No.82100639,No.82200630,and No.81970526;Postdoctoral Scientific Research Foundation of Shanghai Ninth People’s Hospital,Shanghai Jiao Tong University School of Medicine,No.202401023;Clinical Research Program of Ninth People’s Hospital,Shanghai Jiao Tong University School of Medicine,No.JYLJ202124;Shanghai Municipal Commission of Health and Family Planning,No.20244Y0195 and No.20234Y0132;the Fundamental Research Program Funding of Ninth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,No.JYZZ162;Science Foundation of Xinjiang Uygur Natural Autonomous Region,No.2022D01F17.
BACKGROUND Liver cirrhosis and portal hypertension(PHT)can lead to lymphatic abnormalities and coagulation dysfunction.Because lymphangiogenesis may relieve liver cirrhosis and PHT,the present study investigated the g...
关键词:Portal hypertension CIRRHOSIS LYMPHANGIOGENESIS PLATELETS Vascular endothelial growth factor C 
Plates, Beams and Shells Reinforced by CNTs or GPLs: A Review on Their Structural Behavior and Computational Methods
《Computer Modeling in Engineering & Sciences》2025年第2期1351-1458,共108页Mohammad Javad Bayat Amin Kalhori Kamran Asemi Masoud Babaei 
Since the initial observation of carbon nanotubes(CNTs)and graphene platelets(GPLs)in the 1990 and 2000s,the demand for high-performance structural applications and multifunctional materials has driven significant int...
关键词:Graphene platelets carbon nanotubes functionally graded materials hybrid composites mechanical analyses PLATES SHELLS BEAMS 
Preservation of a youthful path to evergreen platelets?
《Cell Research》2025年第2期93-94,共2页Sten Eirik W.Jacobsen 
The enhanced myeloid lineage bias of old hematopoietic stem cells(HSCs)has been implicated to underpin the compromised immunity observed upon aging.In a recent paper in Cell,Poscablo and coworkers now present experime...
关键词:PLATELETS IMMUNITY HEMATOPOIETIC 
Research progress on platelets in glioma
《Chinese Medical Journal》2025年第1期28-37,共10页Mingrong Zuo Tengfei Li Zhihao Wang Yufan Xiang Siliang Chen Yanhui Liu 
supported by the Sichuan Science and Technology Program(No.2023YFQ0002);the internal research funds in West China Hospital of Sichuan University(No.19HXCX009);the Medical Science and Technology Project of Sichuan Health Commission(No.21PJ033).
Gliomas are the most common primary neuroepithelial tumors of the central nervous system in adults,of which glioblastoma is the deadliest subtype.Apart from the intrinsically indestructible characteristics of glioma(s...
关键词:GLIOMA Tumor-educated platelet INTERACTION DIAGNOSIS Biomimetic membrane 
Interest of Non-Invasive Methods to Predict Esophageal Varices in Cirrhotic Patients in Togo
《Open Journal of Gastroenterology》2024年第12期439-446,共8页Laté Mawuli Lawson-Ananissoh Mawunyo Henoc Gbolou Yendoukoa Yves Kanake Diane Laure Moumeni Lidawu Roland-Moïse Kogoe Debehoma Venceslas Redah Aklesso Bagny 
Background: upper digestive endoscopy is the best method for detecting esophageal varices, but its invasiveness and cost make it inaccessible to certain social classes. Aim: to evaluate the performance of non-invasive...
关键词:Esophageal Varices SPLEEN PLATELETS TOGO 
Apoptosis-resistant megakaryocytes produce large and hyperreactive platelets in response to radiation injury
《Military Medical Research》2024年第6期797-817,共21页Chang-Hong Du Yi-Ding Wu Ke Yang Wei-Nian Liao Li Ran Chao-Nan Liu Shu-Zhen Zhang Kuan Yu Jun Chen Yong Quan Mo Chen Ming-Qiang Shen Hong Tang Shi-Lei Chen Song Wang Jing-Hong Zhao Tian-Min Cheng Jun-Ping Wang 
supported by the Key Program of the National Natural Science Foundation of China(81930090);the National Science Foundation for Distinguished Young Scholars of China(81725019);the National Natural Science Foundation of China(32171104,82273571,and 81874256);the Chongqing Natural Science Foundation(2023NSCQ-MSX0687,CSTB2023NSCQ-JQX0015,and cstc2015jcyjys10001);the Chongqing Talent Program(CQYC20220511002).
Background:The essential roles of platelets in thrombosis have been well recognized.Unexpectedly,thrombosis is prevalent during thrombocytopenia induced by cytotoxicity of biological,physical and chemical origins,whic...
关键词:Radiation injury THROMBOCYTOPENIA Platelet size Platelet hyperreactivity Megakaryocytes(MKs) 
Harnessing the power of bioprinting for the development of next-generation models of thrombosis
《Bioactive Materials》2024年第12期328-344,共17页Yanyan Liu Tao Huang Nicole Alexis Yap Khoon Lim Lining Arnold Ju 
supported by the National Health and Medical Research Council(NHMRC)of Australia(APP2003904-L.A.J.);NSW Cardiovascular Capacity Building Program(Early-Mid Career Researcher Grant-L.A.J.,H22/98586-K.L.);MRFF Cardiovascular Health Mission Grants(MRF2016165-L.A.J.,MRF2023977-L.A.J.);MRFF Early to Mid-Career Researchers Grant(MRF2028865-L.A.J.);NSW Government Boosting Business Innovation Program(BBIP)International Stream(L.A.J.);National Heart Foundation Vanguard Grant(106979-L.A.J.);Office of Global and Research Engagement(International Sustainable Development Goal Program-L.A.J.);a Snow Medical Research Foundation Fellow(2022SF176);a National Heart Foundation Future Leader Fellow Level 2(105863);an Australian Research Council Future Fellow(FT230100249).
Thrombosis,a leading cause of cardiovascular morbidity and mortality,involves the formation of blood clots within blood vessels.Current animal models and in vitro systems have limitations in recapitulating the complex...
关键词:BIOPRINTING THROMBOSIS MICROFLUIDICS MECHANOBIOLOGY PLATELETS 
Immobilization of a Metal-Organic Framework on a Nanofiber Membrane as Artificial Platelets for Efficient Hemostasis
《Advanced Fiber Materials》2024年第5期1456-1469,共14页Binglin Bie Zhanglong Zhu Yonggang Lv 
supported by the National Natural Science Foundation of China(U23A2070 and 22201223);Chutian Scholar Foundation of Hubei Province and Natural Science Foundation of Hubei Province,China(2022CFA023).
Medical hemostatic gauze is one of the most common agents for bleeding management used in pre-hospital care and clinical treatment.An ideal hemostat requires the features including fast coagulation ability,high biocom...
关键词:Noncompressible hemostasis Immobilization of metal-organic frameworks Artificial platelets Nanofiber membrane 
Platelet-based bioactive systems guided precision targeting and immune regulation for cancer therapy
《Nano Research》2024年第9期8269-8284,共16页Xinyi Cai Long Qiu Zhenying Diao Lintao Cai Ting Yin Hong Pan 
supported by the National Key Research and Development Program of China(Nos.2022YFC2402400 and 2023YFA0915400);Guangdong Provincial Key Area R&D Program(No.2020B1111540001);the Natural Science Foundation of Guangdong Province(Nos.2024A1515010825,2024A1515030063,2022A1515010780,and 2022A1515011337);Guangdong Province Universities and Colleges Characteristic Innovation(No.2021KTSCX036);Traditional Chinese Medicine Research Project of Guangdong Province Traditional Chinese Medicine Bureau(No.20221206);Shenzhen Medical Research Fund(No.A2303057),Discipline Construction Project of Guangdong Medical University(No.4SG24015G);Construction Project of Nano Technology and Application Engineering Research Center of Guangdong Medical University(No.4SG24179G);Funds for PHD researchers of Guangdong Medical University in 2024.
The antitumor effects of conventional drug carriers are often attenuated and limited in application by biological barriers associated with tumor heterogeneity and resistance brought about by low tumor immunogenicity.W...
关键词:PLATELETS bionic targeting immune modulation precision therapy deep penetration 
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