彩超与GGT联合检测对酒精依赖患者酒精肝的诊断价值  

Diagnosis Value of Colour Ultrasonic Combined with GGT Detection in Alcoholic Liver of Patients with Alcohol Dependence

作　　者：刘榴[1,2] 黄鹏[1,3] 朱秀梅[1,4] 谢锐君[1,2] 袁源香[1,2] 

机构地区：[1]广东省广州市惠爱医院 [2]广州医科大学附属脑科医院心电超声科,广东广州510370 [3]广州医科大学附属脑科医院物质依赖科,广东广州510370 [4]广州医科大学附属脑科医院检验科,广东广州510370

出　　处：《现代生物医学进展》2015年第26期5143-5145,共3页Progress in Modern Biomedicine

基　　金：江门市科技计划项目基金项目(20140200053251)

摘　　要：目的:研究分析彩超和谷氨酰转肽酶(GGT)联合检测对酒精依赖患者酒精性脂肪肝诊断的临床意义。方法:对2013年5月-2014年4月于我院住院并诊断为酒精依赖的患者39例(研究组)行肝脏彩超及GGT检测,另选取同期来源于本院职工、进修医护人员40例为对照组,对其结果进行分析。结果:研究组血清GGT为(189.95±226.52)U/L,显著高于对照组的(26.85±18.94)U/L,差异有统计学意义(t=4.54,P<0.001);研究组中彩超诊断为脂肪肝者的GGT水平与非脂肪肝者有明显差异(P<0.05),且高于对照组中的脂肪肝者,差异有统计学意义(P<0.05)。结论:对于酒精依赖患者,血清GGT是敏感性较高的检测指标,GGT的检测有利于酒精性疾病的早期发现。彩超与GGT联合检测能提高临床对酒精性脂肪肝的检出率。Objective： To investigate the clinical value of colour ultrasonic combined with glutamyl transpeptidase （GGT） detection in the diagnosis of alcoholic fatty liver of patients with alcohol dependence. Methods： A total of 39 patients with alcohol dependence, who were admitted to Guangzhou Huiai Hospital from May 2013 to April 2014, were chosen as study group; the other 40 healthy people from the hospital staff and training medical personnel, as control group. The two groups were detected with liver colour ultrasonic and GGT test, and the detection results were analyzed. Results： The serum GGT level （189.95± 226.52 U/L） in the study group was significantly higher than that（26.85：l： 18.94 U/L） in the control group, the difference was statistically significant（t=4.54, P〈0.001）; There were significant differences in the level of GGT between the patients with alcoholic fatty liver and the patients with non alcoholic fatty liver in the study group（P〈0.05）, which was significantly higher than the patients with alcoholic fatty liver in the control group the difference was statistically significant （P〈0.05）. Conclusion： Colour ultrasonic combined with GGT detection can enhance the clinical detection rate of alcoholic fatty liver. Serum GGT is a high sensitivity detection index for the patients with alcohol dependence, and the GGT detection is helpful for the discovery of early alcoholic disease.

关 键 词：GGT 彩超 酒精性脂肪肝 酒精依赖 

分 类 号：R575.5[医药卫生—消化系统]