PRP对微螺钉种植支抗加载后不同时期周围骨组织变化的实验研究  

An experimental study on change of surrounding bone tissue in different periods after micro-screw implant anchorage loaded with PRP

作　　者：张燎[1] 于宝军[2] 

机构地区：[1]山东省泰安市口腔医院正畸科,271000 [2]江苏省淮安市淮阴医院口腔科

出　　处：《中国口腔种植学杂志》2015年第3期106-110,F0002,共6页Chinese Journal of Oral Implantology

基　　金：山东省泰安市科技发展计划(20103073)

摘　　要：目的：对比在植入微螺钉种植体支抗（MIA）时使用PRP混合物对种植体周围骨形成过程的影响。方法：选用8只成年健康杂种犬,雌雄不分,体重为8~17kg,随机分为等量4组,每组2只。选择犬上颌左右磨牙区的颊侧,沿近远中方向分别植入2枚植体加力互为支抗,按随机原则一枚放置PRP混合物,另一枚为空白对照,分别于术后1周、4周、8周、12周将动物处死获取标本,在显微镜下观察并进行BIC的测量、分析。结果：术后4、8周,实验组于对照组BIC有显著行差异,且实验组BIC较对照组明显增高。结论：使用PRP混合物在植入微螺钉种植体术后4、8周对种植体周围骨形成有明显促进作用。Objective： To compare the change of peri-implant bone formation process in the implantation of micro-screw implant anchorage （MIA） whether to use a PRP mixture. Method： Selection of eight adult mongrel dogs, regardless of male and female, weight 8-17kg, were randomly divided into 4 groups of the same amount, 2 in each group. Choosing a dog bilateral maxillary molar area of buccal, along mesiodistal direction were implanted into two explants anchorage each other, according to the principle of random one placed PRP mixture, and the other one for the blank control, application of force, re- spectively, after 1 week, 4 weeks, 8 weeks, 12 weeks, the animals were sacrificed to obtain samples, then go BIC measurement and analysis with observed under the microscope. Results： At 4 and 8 weeks after surgery, there are have significant differences between the experimental group and the control group , and the experimental group BIC was significantly higher than the control group. Conclusion： The use of PRP mixture at 4 and 8 weeks after implantation of micro-screws can obviously promote bone formation around the implant.

关 键 词：PRP混合物 微螺钉种植体 骨形成 犬 

分 类 号：R783[医药卫生—口腔医学]