甲状腺呈胸腺样分化癌的临床分析  

The clinical analysis of thyriod carcinoma showing thymus-like differentiation

作　　者：梁锦辉[1] 黄河浪[1] 李莉[1] 罗海林[1] 黄梅[1] 张翔[1] 高山[2] 毛谓东 

机构地区：[1]汉中市中心医院耳鼻咽喉头颈外科,陕西汉中723000 [2]汉中市中心医院病理科 [3]汉中市中心医院放疗科

出　　处：《临床耳鼻咽喉头颈外科杂志》2015年第19期1736-1738,共3页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的:探讨甲状腺呈胸腺样分化癌(CASTLE)的临床诊断、治疗及预后,提高对CASTLE的认识。方法:对6例CASTLE患者行Ⅵ区淋巴结清扫+病灶所在甲状腺叶及峡部切除术。术后除1例68岁患者外,其余患者术后第3周行颈前区放疗60Gy,予以顺铂化疗5个疗程,每次间隔2周。并坚持口服尤甲乐。结果:所有患者随访期间均存活,无复发和转移。结论:CASTLE的诊断及鉴别诊断有赖于组织病理学及免疫组织化学检测,手术是其主要治疗手段。CASTLE是一种少见的甲状腺恶性肿瘤,进展缓慢,预后较好。Objective：To investigate the clinical diagnosis, treatment and prognosis of carcinoma showing thymus-like differentiation （CASTLE） of thyroid, and to improve the understanding of CASTLE. Method： In 6 patients with CASTLE, we performed region VI lymph node dissection, the lesion resection of thyroid lobe and isthmus. After the operation, except one case of 68 years old patient, the rest patients were treated with radiotherapy 60 Gy in anterior cervical region after third week of operation and 5 courses of chemotherapy with cisplatin, each interval of 2 weeks. Insist on the oral Euthyrox. Result：All patients were alive without recurrence and metastasis. Conclusion：The diagnosis of CASTLE depends on the histology and immunohistochemistry. Operation was the main treatment. CASTLE is a rare type of thyroid carcinoma with slow progress and good prognosis.

关 键 词：甲状腺肿瘤 胸腺瘤 淋巴结清扫术 

分 类 号：R736.1[医药卫生—肿瘤]