足月新生儿眼轴长度测量及分析  

Measurement and analysis of the axial length of full-term newborns

作　　者：毛剑波[1] 李丽红[2] 洪明胜[1] 李娜[2] 褚梦琪 沈丽君[1] 

机构地区：[1]温州医科大学附属眼视光医院,325027 [2]云南省昆明市妇幼保健院,650031

出　　处：《中华眼视光学与视觉科学杂志》2015年第9期558-560,共3页Chinese Journal Of Optometry Ophthalmology And Visual Science

摘　　要：目的 通过测量足月新生儿眼轴长度（AL）,探讨正常新生儿AL的正常范围、特点及AL与胎龄、出生体质量等的关系.方法 横断面研究.选取2011年7月至2014年1月出生的足月新生儿750例,应用A超测量出生1～3 d新生儿双眼的AL.观察不同性别、胎龄、出生体质量、分娩方式足月新生儿的AL分布情况.采用t检验、单因素方差分析、Pearson相关分析及多元线性回归进行数据处理.结果 750例（1 500眼）足月新生儿的右眼和左眼AL分别为（16.54±0.59）mm、（16.54±0.56） mm,差异无统计学意义.以左右眼AL均值作为该新生儿的AL,足月新生儿AL平均值为（16.54±0.57）mm,95％CI为16.50～16.58 mm,其中男性新生儿AL为（16.55±0.57）mm,女性新生儿AL为（16.53±0.57）mm,差异无统计学意义.胎龄为37、38、39、40、41周组新生儿（各胎龄组分别为150例）的平均AL分别为（16.14±0.43）mm、（16.50±0.32）mm、（16.51±0.40）mm、（16.70±0.69）mm、（16.86±0.67）mm.出生体质量2.5～、3.0～、3.5～＜4.0 kg组新生儿AL分别为（16.34±0.52）mm、（16.52±0.51）mm、（16.73±0.61）mm.AL与胎龄、出生体质量均呈正相关（r=0.402、0.249,P＜0.01）.与性别、分娩方式无相关性.将胎龄、出生体质量等因素纳入多元回归模型,得出回归方程：AL=10.391＋0.151×胎龄.结论 正常足月新生儿平均AL为（16.54±0.57）mm.AL随着胎龄、出生体质量的增加而延长,而与性别、分娩方式无关。Objective To measure the full-term newborns axial length （AL）, and to study the associations with gestational age, birth weight, delivery mode, gender.Methods This was a cross-sectional study.A subset of 750 full-term neonates （1 500 eyes） were included.The age of neonates ranged from 1 to 3 days.AL was measured quantitatively by A ultrasound.Associations with atenatal factors were also studied, which include gender, gestational age, birth weight, and delivery mode.Data were analyzed using t test, one-way ANOVA, Pearson correction and multivariable linear regression analysis.Results No significant difference between the right eyes 16.54±0.59 mm and the left eyes 16.54± 0.56 mm AL was found.The mean value of left and right eye AL was defined as the neonatal AL.Mean longitudinal AL was 16.54±0.57 mm, 95%CI 16.50～16.58 mm.There were 376 male neonates （50.1%） 374 female neonates （49.9%）, whose AL were 16.55±0.57 mm and 16.53±0.57 mm.The mean AL of different gestational age from 37 weeks to 41 weeks were 16.14±0.43 mm, 16.50±0.32 mm, 16.51±0.40 mm, 16.70±0.69 mm, 16.86±0.67 mm.Both birth weight and gestational age were positively correlated with AL （r=0.402, 0.249, P〈0.01）.The mean AL of different birth weight from 2.5～, 3.0～, 3.5～〈4.0 kg were 16.34±0.52 mm, 16.52±0.51 mm, 16.73±0.61 mm.AL had no correlation with gender, delivery mode.Multiple linear regression analysis showed the regression equation： AL=10.391＋0.151×gestational age.Conclusion The full-term newbom AL was 16.54±0.57 mm.There was no significant difference between the right eyes and the left eyes AL.Gestational age and birth weight were positively correlated with AL.

关 键 词：眼轴长度 婴儿 新生 出生体重 足月分娩 

分 类 号：R770.4[医药卫生—眼科]