磁共振图像中磁量图技术研究进展  

Research Progress of Quantitative Susceptibility Mapping in MRI

作　　者：王帅[1] 段昶[1] 张萍[2] 王春梅[3] 刘想[1] 李鸿升[1] 程建[1] 

机构地区：[1]电子科技大学电子工程学院,成都611731 [2]电子科技大学光电信息学院,成都611731 [3]武汉工程大学计算机科学与工程学院,武汉430205

出　　处：《生物医学工程学杂志》2015年第5期1131-1134,共4页Journal of Biomedical Engineering

基　　金：国家自然科学基金资助项目(61201271;61308102);四川省科技支撑计划资助项目(2014GZX0009);四川省省院科技合作计划资助项目(2012JZ0001);中央高校基本科研业务费资助项目(ZYGX2013J019);中国博士后科学基金资助项目(2013M531946)

摘　　要：磁化率是一种描述物质内在磁介质属性的物理量,反映的是物质磁化强度与外界所施加的磁场之间的关系。磁量图(QSM)是一种可在体内对组织宏观磁化率定量的磁共振图像(MRI)技术。QSM可清楚显示具有顺磁性或者反磁性组织的解剖结构。QSM算法是解决从测量到的组织磁场中通过非常规的单位偶极子反卷积获得磁化率分布这一病态问题的方法。研究者们提出了多种基于多角度扫描和面向临床单角度扫描的QSM算法来解决这个病态问题。本文通过介绍QSM的基本概念、系统分析当前多种QSM算法、简要介绍QSM的研究进展,旨在促进QSM技术发展和临床应用。Magnetic susceptibility is an intrinsic physical quantity which describes the relationship between material magnetization and applied external magnetic field. Quantitative susceptibility mapping （QSM） is an MRI technology which can quantify the buck magnetic susceptibility of tissue in vivo. It is particularly effective at elucidating anatomy with paramagnetic or diamagnetic components. QSM technology is a method for solving the ill-pose problem of un- conventional de-convolution of the measured tissue magnetic field with the unit magnetic dipole field to obtain the susceptibility source map. Many multi orientation scan based QSM and clinically acceptable single orientation QSM methods have been proposed to solve this ill-posed problem. In this paper, the QSM concept is introduced and the various QSM methods are systematically categorized and discussed. The aim of this paper is to summarize the current research progress of QSM, popularize the knowledge of QSM and promote the improvements and the rational appli- cation of QSM in clinical field.

关 键 词：磁量图 磁化率 病态 逆问题 反卷积 在体定量 

分 类 号：TP391.41[自动化与计算机技术—计算机应用技术]