补锌干预对改善孕妇营养状况和生育结局的研究  

Study of zinc supplementation on improving the nutritional status and birth outcomes of pregnant women

作　　者：邹晓燕[1] 

机构地区：[1]山东省济南市第五人民医院妇产科,山东济南250022

出　　处：《临床医药文献电子杂志》2015年第25期5181-5182,共2页Electronic Journal of Clinical Medical Literature

摘　　要：目的探讨补锌干预对孕妇锌营养状况和新生儿生长发育的影响。方法选择2014年1月~2014年10月在济南市第五人民医院定期孕检的孕龄小于12周的孕妇256例,分为预防干预组和对照组各128例,预防干预组选择自愿接受口服含锌胶囊且健康的孕妇作为干预对象,对照组选择仅服用安慰剂的健康孕妇。分别在孕12周、孕27~29周及产前抽取孕妇静脉血,测定其锌浓度。于产后24 h测定新生儿生长发育指标。结果孕早期干预组和对照组全血锌浓度无显著性差异,而孕中晚期干预组全血锌浓度比对照组的高,差异有统计学意义（P〈0.05）。干预组新生儿的出生体重、头围、身长及1分钟Apgar评分均大于对照组,差异有统计学意义（P〈0.05）。结论对孕妇每日补充适量的含锌胶囊可改善孕妇孕中、晚期的锌营养状态,显著改善新生儿的生长发育状况。Objective To investigate the influence of zinc intervention to the pregnant woman of zinc nutritional status and neonatal growth and development. Methods 2014 January to 2014 October, less than 12 weeks in the Fifth People＇s Hospital of Ji＇nan city regularly pregnant examination gestational age of 256 pregnant women, divided into preventive intervention group and control group with 128 cases in each group, preventive intervention group choose voluntarily accept oral zinc capsules and healthy pregnant women as control group intervention objects, select only the placebo healthy pregnant women. Respectively at 12 weeks of pregnancy, pregnancy 27~29 weeks pregnant and prenatal extraction of venous blood, the determination of the concentration of zinc. The measurement in a postpamma 24h newborn growth and development indicators. Results early pregnancy intervention group and control group, no significant difference of blood zinc concentration, and late pregnancy in the intervention group of blood zinc concentration higher than that of the control group, there was significant difference. The intervention group neonatal birth weight, head circumference, length and 1 minute Apgar score were higher than the control group, there was significant difference. Conclusion Zinc nutritional status of pregnant women conclusion daily supplement of proper amount of zinc containing capsule can improve pregnancy, late, significantly improve the growth and development of neonates.

关 键 词：锌干预 孕妇 新生儿 营养状况 生长发育 

分 类 号：R153.1[医药卫生—营养与食品卫生学]