磁共振弥散加权成像在胰腺癌放疗中的研究进展  

Research progress of diffusion-weighted magnetic resonance imaging in radiotherapy of pancreatic cancer

作　　者：韩若冰[1] 王轩[1] 夏廷毅[1] 

机构地区：[1]空军总医院肿瘤放疗科,北京100042

出　　处：《肿瘤研究与临床》2015年第9期643-646,共4页Cancer Research and Clinic

摘　　要：近年来，胰腺癌发病率在全世界范围内呈明显上升趋势，病死率较高。胰腺癌早期缺乏高敏感性及特异性的诊断方法，手术切除率仅10%～20%，手术死亡率高，远期疗效差，5年生存率不到5%。目前研究显示放疗可不同程度地改善胰腺癌患者的生活质量，提高肿瘤局部控制率，延长患者的总体生存时间。弥散加权成像（DWI）作为磁共振成像（MRI）的一种功能成像技术，是唯一可以反应细胞水平变化的影像手段。文章对DWI应用于胰腺癌放疗方面的研究进展进行综述。In recent years, the incidence of pancreatic cancer shows rising trend and higher mortality. Pancreatic cancer lacks early diagnostic methods with high sensitivity and specificity, and the surgical resection rate is 10 %-20 % with high operation mortality, poor long-term curative effect and less than 5 %survival rate within 5 years. At present, researchers indicate that radiotherapy can improve the quality of life, increase tumor local control rate and prolong the overall survival time of patients with pancreatic cancer in different levels. Diffusion weighted imaging （DWI）, as a functional imaging technology of magnetic resonance imaging （MRI）, is the only way to react cell levels. This paper will summarize the application of DWI in radiotherapy of pancreatic cancer.

关 键 词：胰腺肿瘤 磁共振成像 弥散 表观弥散系数 放射疗法 

分 类 号：R735.9[医药卫生—肿瘤] R730.55[医药卫生—临床医学]