辐射旁效应及其机制研究进展  

Advances in Research of Radiation Induced Bystander Effect and Its Mechanism

作　　者：张朝宁[1] 李金田[1] 刘永琦[1] 

机构地区：[1]甘肃中医药大学,兰州730000

出　　处：《辐射防护通讯》2015年第3期19-24,共6页Radiation Protection Bulletin

基　　金：国家自然科学基金项目(81460695)

摘　　要：辐射旁效应是未受辐射的细胞表现出与受辐射的细胞相同或相似的生物学反应的现象。本文简要介绍了生物体外、体内辐射旁效应的研究现状,简述辐射旁效应中有关时间-效应方面的研究,以及辐射旁效应产生机制的研究进展。Radiation induced bystander effect is a phenomenon that non-radiated cells have the same or similar biological reaction with those radiated cells. A large nmnber of studies show the objective existence of this ef- fect. The paper briefly reviews its research status, in vitro and in vivo, and discusses studies on time-effect and research progress of generation mechanism in the respect.

关 键 词：辐射旁效应 体内研究 体外研究 细胞间隙连接通讯 细胞介质 

分 类 号：R730.2[医药卫生—肿瘤]