根管治疗术一次法与多次法治疗感染根管治愈率的Meta分析  

Healing Rate of Single- versus Multiple-visit Root Canal Treatment for Teeth with Infected Root Canals: A Meta-analysis

作　　者：张洋洋[1] 梁学萍[1] 赵今[1] 

机构地区：[1]新疆医科大学附属口腔医院牙体牙髓科,乌鲁木齐830054

出　　处：《中国循证医学杂志》2015年第10期1202-1206,共5页Chinese Journal of Evidence-based Medicine

摘　　要：目的系统评价根管治疗术一次法与多次法治疗感染根管的治愈率。方法计算机检索PubMed、EMbase、EBSCO、MEDLINE、The Cochrane Library(2015年第3期)、CNKI、VIP、CBM和WanFang Data数据库,搜集根管治疗术一次法与多次法比较治疗感染根管的相关随机对照试验(RCT),检索时限均从建库至2015年3月。由2位评价员独立筛选文献、提取资料并评价纳入研究的偏倚风险后,采用RevMan 5.3.5软件进行Meta分析。结果共纳入9个RCT,共1 146颗患牙。Meta分析结果显示:在根管治疗术治疗感染根管的治愈率方面,一次法为88.98%,多次法为85.61%,两组差异无统计学意义[OR=1.36,95%CI(0.95,1.96),P=0.09]。结论基于当前可得证据,根管治疗术一次法与多次法治疗感染根管的治愈率相当。受纳入研究数量所限,上述结论尚需开展更多高质量研究予以验证。Objective To systematically review the healing rate of single- versus multiple-visit root canal treatment for teeth with infected root canals. Methods PubMed, EMbase, EBSCO, MEDLINE, The Cochrane Library（Issue3, 2015）, CNKI, VIP, CBM and WanFang Data databases were searched from inception to March 2015, to collect randomized controlled trials（RCTs） concerning single- versus multiple-visit root canal treatment for teeth with infected root canals. Two reviewers independently screened literature, extracted data, and assessed the risk of bias of included studies. Then meta-analysis was performed using RevMan 5.3.5 software. Results A total of 9 RCTs involving 1 146 teeth were included. The results of meta-analysis showed that： the healing rates were 88.98% in the single-visit group,and 85.61% in the multiple-visit group, respectively. There were no significant difference between two groups（OR=1.36,95%CI 0.95 to 1.96, P=0.09）. Conclusion Current evidence shows that, the healing rate of single- and multiple-visit root canal treatment is similar for infected root canals. Due to the limited quantity of included studies, more high quality studies are needed to validate the above conclusion.

关 键 词：根管治疗术 感染根管 治愈率 系统评价 META分析 随机对照试验 

分 类 号：R781.05[医药卫生—口腔医学]