海口地区123例口腔黏膜下纤维性变的临床调查分析  

Investigative analysis of 123 patients with oral submucous fibrosis in Haikou area

作　　者：杜永秀[1] 翦新春[1] 周婷[1] 王彬娉[1] 程亚楠[1] 黄迈文 徐普[1] 

机构地区：[1]中南大学湘雅医学院附属海口医院·海南省口腔医学中心口腔黏膜病科,海口570208

出　　处：《中国医师杂志》2015年第9期1286-1289,共4页Journal of Chinese Physician

基　　金：2014年海口市医学重点学科资助项目

摘　　要：目的 研究海南省海口地区咀嚼槟榔对口腔黏膜下纤维性变的影响因素.方法 对海口市人民医院治疗的123例口腔黏膜下纤维性变（OSF）患者的年龄、性别、籍贯、咀嚼槟榔种类及时间、患病主要症状、对咀嚼槟榔危害性的认知度等临床资料进行分析.结果 （1）123例OSF患者平均年龄36.5岁,最常见为30～50岁年龄组,咀嚼槟榔者主要为男性,女性多为海南黎族;（2）嚼食干槟榔者5年内OSF发病率较嚼食鲜槟榔者高,两者差异有统计学意义（x2=18.79,P＜0.01）,而同期两者共同发病率与干、鲜槟榔混嚼者发病率差异无统计学意义（P＞0.05）;（3）部分OSF患者初诊症状为黏膜刺激痛、黏膜苍白、张口受限和纤维条索;（4）123例患者中有61例（占49.59％）了解咀嚼槟榔对口腔健康有害,但大多不能使自己改变生活习惯.结论 咀嚼槟榔习惯在海口地区男性居多,女性多为海南黎族,部分患者不能克服咀嚼槟榔的生活习惯;嚼食干槟榔OSF的发病率大于嚼食鲜槟榔的发病率,嚼食干槟榔比嚼食鲜槟榔更易致病.Objective To explore the influential facts of betel quid chewing for patients with oral submucous fibrosis （OSF） in Haikou,Hainan Province.Methods One hundred and twenty three patients in the Haikou City People＇s hospital were investigated regarding their clinical information,including age,sex,origins,kinds and time of betel nut chewing,obvious clinical features,cognition for its harmfulness and so on.Results （1）The mean age was 36.5 years old,the most common patients were the group between the ages of 30 and 50 among 123 patients,male preferred to chewing betel nut,the female fond of betel nut were mostly Li minority women.（2）People chewing the dry betel nut had the higher incidence than the ones who prefer the fresh in five years.The both were significant difference （x2 =18.79,P 〈0.01）,however,the incidence difference between the patients at the same time and the ones chewing kinds of betel nut was not significant （P 〉 0.05）.（3）The early clinical features of some OSF patients included stimulating pain,mucosal blanching,gradual inability to open the mouth and fibrous bands.（4）Although 61 patients （49.59%） knew about the harmfulness of betel nut chewing for their oral health,they could not change their lifestyle.Conclusions Male prefers to chewing betel nut,the female fond of betel nut are mostly Li minority women in Haikou area,the parts of patients could not overcome the habit ofchewing betel nut; people chewing the dry betel nut has the higher incidence than the ones who prefer the fresh＇s at early period,and of the two the former prone to disease than the latter.

关 键 词：口腔黏膜下纤维化/流行病学/病因学 槟榔/副作用 数据收集 

分 类 号：R781.5[医药卫生—口腔医学]