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机构地区:[1]湘潭市口腔医院,湖南省湘潭411100 [2]湘潭市卫生局 [3]湘潭市中心医院 [4]中南大学湘雅附二院 [5]北大口腔医学院
出 处:《中国医师杂志》2015年第9期1290-1295,共6页Journal of Chinese Physician
摘 要:目的 了解口腔黏膜下纤维性变的发病原因,采取相应的应对措施,做好口腔黏膜下纤维性变防治工作.方法 采取整群抽样,按Pindborg制定的诊断标准,对湘潭市雨湖区不同类型57个单位的11 046例进行了咀嚼槟榔致口腔黏膜下纤维性变(OSF)的流行病学调查.结果 确诊OSF 335例,患病率30.33‰,并存口腔癌4例,口腔癌并存率11.94‰;全部OSF患者均有嚼槟榔史,不嚼槟榔者(含有烟、酒、辣嗜好者)未发现OSF患者;OSF患病率在嚼槟榔嗜好的人群中无性别和年龄差异;OSF患病率与日平均咀嚼槟榔剂量和咀嚼槟榔的年限相关(r=0.28828,P<0.01);使用不同槟榔添加剂OSF患病率差异有统计学意义;不同嗜好配伍组配对标化检验,7组中有6组患病率差异无统计学意义(P>0.05),而只吃辣椒的本地人(内对照组1 329例)和外地人(外对照组698例)无OSF患者.结论 嚼槟榔是湘潭人患OSF的主要因素,OSF癌患病率低于国外.Objective To understand oral submucous fibrous (OSF) because the hair cause of disease and the quantitative corresponding measures,do a good job in OSF prevention and control work.Methods The quantitative cluster sampling,according to the diagnostic criteria of the development of the Pindborg,yuhu in Xiangtan city of different types of 57 units of 11 046 people to chew areca cause OSF epidemiological investigation.Results OSF 335 diagnosis example,the prevalence rate of 30.33‰,4 cases were oral cancer,oral cancer coexist rate was 11.94‰; All OSF patients had a history of betel nut,no chewing betel nut (containing the cigarette,wine,and spicy aficionados) were not found in patients with OSF; Of OSF prevalence in the chewing hobby was no differences in sex and age in the crowd; OSF prevalence of high and low with length of fixed number of year of average chewing betel nut dose and chewing betel nuts were closely related(r =0.28828,P 〈 0.01) ; OSF prevalence was different from eating betel nut additive that had a very significant difference.Different hobbies compatibility with standardized test,7 incidence group had 6 group without significant difference,but people only eat chili can (in the control group,1 329) and outsiders no OSF patients (control group,698).Conclusions Survey results confirm that chewing betel nut is the main factor of Xiangtan people of OSF,and OSF carcinoma prevalence is lower than abroad.
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