子宫颈小细胞神经内分泌癌的临床与病理  

CLINICAL AND PATHOLOGICAL ANALYSIS OF SMALL--CELL NEUROENDOCRINE CARCINOMA OF THE CERVIX

作　　者：柴德峰[1] 于国[1] 傅才英[1] 叶惠方[1] 李冬平[1] 

机构地区：[1]解放军总医院

出　　处：《解放军医学杂志》2002年第8期738-739,共2页Medical Journal of Chinese People's Liberation Army

摘　　要：收集分析了子宫颈神经内分泌癌 8例 ,其中 ,Ⅰa期 1例 ;Ⅰb期 2例 ;Ⅱa期 2例 ;Ⅱb期 1例 ;Ⅲa期 1例 ;Ⅲb期 1例。3例进行了广泛子宫切除及盆腔淋巴结清扫术 ,5例进行了放射治疗。5例死亡前分别存活 13～38个月 ,平均 19个月。仍存活的 3例分别为治疗后3、4、5个月 ,其中 1例已发生肾转移。结果提示 ,子宫颈小细胞神经内分泌癌是一种罕见的子宫颈恶性程度高的肿瘤 ,易发生早期转移 ,预后差 ;早期病例应采取广泛子宫及盆腔淋巴结清扫术 ,并进行放疗或化疗。晚期病例只能行化疗或放射治疗。To study the clinicopothologic diagnosis and treatment of small cell neuroendocrine carcinoma of the cervix(SCNCC)in relion to its outcome. Eight cases of SCNCC treated within 10 years in our hospital were reviewed and andlyzed retrospectively and followed up in our clinic. The clinical and pathologic classifications were correct, namely:Ⅰa 1,Ⅰb 2,Ⅱa 2, Ⅱb 1; Ⅲa 1 and Ⅲb 1 case. Three early cases had total hysterectomy with all pelvic lymph nodes removed and 5 late cases had radio therapy only.Of them 5 cases died 13～38 months after treatment,averaging 19 months, 3 liviny,for 3,4 and 5 months,respectively,one case, however,with metastasis to kidney.SCNCC is a rare tumor of high malignancy with early metastasis and poor prognosis.It should be recognized early and treated with Wertheim's operation and total removal of pelvic lymph nodes with postoperative radio or chemotherapy. Late cases might be benefited by radio or chemotherapy.

关 键 词：子宫颈小细胞神经内分泌癌 宫颈肿瘤 病理学 SCNCC 临床表现 

分 类 号：R737.33[医药卫生—肿瘤]