温州地区真菌性角膜炎流行病学特征分析  

Pidemiological analysis of fungal keratitis in Wenzhou area

作　　者：王友沛[1] 顾云峰[1] 徐一[1] 毛丽萍[1] 楼永良[2] 

机构地区：[1]温州医科大学附属眼视光医院检验科,浙江温州325027 [2]温州医科大学检验与生命科学院,浙江温州325027

出　　处：《中国卫生检验杂志》2015年第19期3364-3365,3368,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的调查分析温州地区真菌性角膜炎患者的流行病学特征。方法采用回顾性方法分析2009年10月-2014年9月158例本院确诊为真菌性角膜炎的患者及483例对照组患者,分析流行病学特征及其致病危险因素。结果以125例农村居民为主,占79.0%;40岁以上为高发年龄段;9月-次年3月为多发期,发病数为128例(81.0%);多数有明确外伤史(64.6%);菌属鉴定排前2位的病原菌分别为镰刀菌属(47.6%)和曲霉菌属(22.9%)。结论温州地区真菌性角膜炎多发于中老年的男性农村居民,其中9月-次年3月为高发期,且多数有明显诱因,致病菌以镰刀菌属和曲霉菌为主。因此,对于具有发病危险因素的真菌性角膜炎患者,应早期进行积极有效的抗真菌治疗。Objective To study the epidemiological characteristics of patients with fungal keratitis（ FK） in Wenzhou. Methods A total of 158 cases of FK,from October 2009 to September 2014,and 483 control patients were retrospectively reviewed for the risk factors and epidemiological characteristics. Results 125 patients（ 79. 0%） were rural residents. The incidence peak was with the patients above 40 years old. The peak of FK occurred in every September to the next March,there were a total of 128patients（ 81. 0%）. And most of them were with the history of trauma（ 64. 6%）. Bacteria identification of pathogenic fungus ranked the top two for Fusarium spp（ 47. 6%） and Aspergillus species（ 22. 9%）. Conclusion Fungal keratitis mostly occur in the elderly male rural residents in Wenzhou area,and the peak of FK occurred in every September to the next March. Most cases occurred with obvious trigge. The pathogenic bacteria are mainly Fusarium and Aspergillus species. Therefore,the fungal keratitis patients with the risk factors should be actively carried out,and effective in the treatment of early anti fungal.

关 键 词：真菌性角膜炎 流行病学 温州地区 

分 类 号：R77[医药卫生—眼科]