原发性低颅压综合征19例临床分析  

Clinical analysis of 19 cases of spontaneous intracranial hypotension

作　　者：李举[1] 胡珍珠[1] 李可[1] 张尊胜[1] 

机构地区：[1]徐州医学院附属医院神经内科,江苏徐州221000

出　　处：《中国医药科学》2015年第18期137-139,共3页China Medicine And Pharmacy

摘　　要：目的提高对原发性低颅压综合征的认识。方法回顾性分析近5年本院确诊的SIH 19例临床资料,并结合文献对该病的诊治进行讨论。结果 19例均有不同程度的体位性头痛,并可伴有头晕、恶心、呕吐、颈强直,有18例侧卧位腰椎穿刺脑脊液压力低于60mm H2O,蛋白增高11例,WBC增高8例,RBC增高2例,13例行头颅MRI增强检查示弥漫性硬脑膜强化,均采取保守治疗,16例痊愈,3例好转。结论体位性头痛是PIH最典型的症状,弥漫性硬脑膜强化是最常见的影像学表现,PIH预后良好。Objective To deepen understanding of Spontaneous intracranial hypotension. Methods Clinical data of 19 patients who were diagnosed as SIH in our hospital in recent 5 years were analyzed retrospectively.The diagnosis and treatment of this disease were discussed with the assistance of literature. Results All of 19 patients had various degrees of postural headache accompanied with some symptoms including dizziness,nausea,vomiting and neck rigidity.Cerebrospinal fluid pressure of 18 patients with lumbar puncture in a lateral position was below 60 mm H2 O.11 patients had elevated protein,8 had increased WBC and 2 had increased RBC.Enhanced MRI examination typically revealed diffused pachymeningeal enhancement in 13 patients. All patients were received conservative treatment,of whom 16 were cured and 3 were improved. Conclusion Postural headache is the most typical symptom of PIH and diffused pachymeningeal enhancement is the most common imaging finding.PIH has a good prognosis.

关 键 词：原发性低颅压综合征 头痛 影像学 腰穿 

分 类 号：R741[医药卫生—神经病学与精神病学]