不同糖代谢状况缺血性脑卒中患者HbAlc水平与脑动脉病变程度的关系  

Relationship Between HbAIc Levels and Cerebral Arterial Lesions in Patients With Ischemic Stroke With Different Glucose Metabolism

作　　者：詹红艳[1] 杨红英[2] 袁莉[2] 牛春华[2] 王丽英[2] 陈丽丽[2] 

机构地区：[1]唐山市丰润区第二人民医院,063000 [2]唐山市工人医院,063000

出　　处：《中国继续医学教育》2015年第27期49-51,共3页China Continuing Medical Education

基　　金：唐山市科技计划项目(13130251b)

摘　　要：目的研究不同糖代谢状况缺血性脑卒中患者的糖化血红蛋白水平与脑动脉病变程度的关系。方法选取2013年6月～2015年6月唐山市工人医院收治的缺血性脑卒中患者120例,根据糖代谢情况分为正常组（n=20）、异常组（n=65）、糖尿病组（n=35）,比较三组的一般资料、分析Hb Alc水平、脑动脉病变危险因素、脑动脉病变部位及支数。结果三组患者性别、高血压、吸烟、TG、Hcy等方面比较,差异无统计学意义（P〉0.05）,三组患者中饮酒、冠心病、Hb Alc、TC、HDL-C、LDL-C比较,差异有统计学意义（P〈0.05）;三组患者中,正常组脑血管狭窄以轻度为主,前循环多见,单支受累血管多。糖代谢异常组和糖尿病组患者脑血管狭窄以中、重度为主,前后循环和多支受累为主（P〈0.05）。结论不同糖代谢水平影响脑血管病变,Hb Alc水平影响脑动脉病变程度、病变部位和病变支数,是影响脑动脉病变的重要危险因素。ObjectiveTo study the relationship between the level of glycosylated hemoglobin and cerebral arterial lesions in patients with ischemic stroke with different glucose metabolism.Methods 120 cases of ischemic stroke patients were chosen from June 2013 to June 2015 in Tangshan workers hospital, according to glucose metabolism is divided into normal group （n=20） and abnormal group （n=65）, diabetes group （n=35）. To analysis of HbA1c level, risk factors for cerebral artery disease, cerebral artery lesion sites and count of the three groups were compared. ResultsThere were no significant differences in gender, hypertension, smoking, TG, Hcy among the three groups （P〉0.05）, the differences were statistically signiifcant with alcohol, coronary heart disease, TC, HDL-C, HbAlc, LDL-C In the three groups of patients （P〈0.05）. In the patients with abnormal glucose metabolism and diabetes mellitus, cerebral blood vessel stenosis was dominated by moderate and severe cerebral artery stenosis, and the main was the main and the most affected （P〈0.05）.Conclusion Different levels of glucose metabolism affect cerebral vascular lesions and HbAlc level of cerebral artery stenosis, the location of the lesion and lesion count is affect brain artery disease are important risk factors.

关 键 词：糖化血红蛋白 脑动脉病变 糖代谢异常 

分 类 号：R743[医药卫生—神经病学与精神病学]