富血小板血浆与富血小板纤维蛋白联合冻干法研究进展  

Research Progress of Freeze-drying and Combined Application of PRP and PRF

作　　者：刘丽莎[1,2] 张斌[1,2] 李莹[1,2] 

机构地区：[1]哈尔滨医科大学附属第二医院 [2]哈尔滨医科大学中俄医学研究中心硬组织发育与再生研究所,黑龙江哈尔滨150086

出　　处：《口腔医学研究》2015年第10期1047-1049,共3页Journal of Oral Science Research

基　　金：国家自然科学基金(编号:81170960)

摘　　要：手术使用的浓缩血小板是再生医学的创新材料,富血小板血浆(PRP)是第一代富含血小板的浓缩物,已广泛应用于促进软硬组织愈合。富血小板纤维蛋白(PRF)是由法国学者Choukroun等首次提出的新一代血小板浓缩物,较传统富血小板血浆更具有应用优势。冻干法是保存生物制品的常规方法,也是控制支架空隙大小并保存其原有成分的有效手段。本文就于富血小板血浆和富血小板纤维蛋白结合冻干法应用于组织发育与再生作一综述。Platelet concentrates for surgical use are innovative tools of regenerative medicine.Platelet-rich plasma（PRP）is the first generation of platelet concentrate that has been used widely to accelerate soft-tissue and hard-tissue healing.Platelet-rich fibrin（PRF）,a new generation of platelet concentrates,is first described by Choukroun et al.It has been shown to have several advantages over traditional PRP.Freeze-drying is the conventional method to save biological products andis also an effective means to control scaffold pore size and preserve its composition.This article reviewed PRP,PRF,freeze-drying and the combined application in organization development and regeneration.

关 键 词：富血小板血浆 富血小板纤维蛋白 冻干法 

分 类 号：R783.1[医药卫生—口腔医学]