增加体育运动对原发性失眠患者过度觉醒的影响  

Effect of Increasing Physical Exercise on Hyperarousal in Patients with Primary Insomnia

作　　者：王继辉[1] 韩自力[1] 李冠英[1] 吴小立[1] 

机构地区：[1]中山大学附属第三医院精神科,广东广州510630

出　　处：《中山大学学报（医学科学版）》2015年第5期791-796,共6页Journal of Sun Yat-Sen University:Medical Sciences

基　　金：广东省科技计划项目(2009B080701080)

摘　　要：【目的】研究增加体育运动对原发性失眠患者过度觉醒的影响。【方法】51例来自精神科门诊的低体育运动水平原发性失眠患者,随机分为研究组(n=26)和对照组(n=25),两组均给予酒石酸唑吡坦(10 mg,qn)治疗,疗程4周,研究组给予简要的体育运动咨询以提高其体育运动水平。采用过度觉醒量表、睡前觉醒量表评估患者的过度觉醒程度,采用匹兹堡睡眠质量指数和睡眠日志评估患者睡眠情况。【结果】研究组睡前觉醒量表分(15.03±7.87 Vs 6.72±4.42)、睡眠日志的入睡潜伏期(24.73±22.94 Vs 19.04±19.15)及入睡后觉醒时间(24.07±18.22 Vs 17.24±15.44)的改善优于对照组(P<0.01)。【结论】提高体育运动水平可有效减轻原发性失眠患者入睡前过度觉醒状态,并且有利于睡眠的改善。【Objective】 To test the effect of increasing physical exercise on hyperarousal in the patients with primary insomnia.【Methods】 A total of 51 physically inactive patients with primary insomnia from psychiatric clinic department were recruited.Participants were randomly assigned to either intervention group（n = 26）, consisting of medication with Zolpidem Tartrate Tablet plus four-week physical exercise counseling, or control group（n = 30）, consisting of medication with Zolpidem Tartrate Tablet only. The primary outcome was self-report symptom, based on the Hyperarousal Scale（HAS）, Pre-Sleep Arousal Scale（PSAS）,Pittsburgh sleep quality index（PSQI） and sleep diaries（including Sleep Latency-SL, Wake after Sleep Onset-WASO, Sleep Efficiency-SE）which were evaluated on baseline and at the end of the 2nd, 4th week treatment. Continuous variables were evaluated by repeatedmeasures analyses of variance（ANOVA）. 【Results】 The ANOVA showed a significant treatment group × time interaction, and time main effects for the scores of PSAS, SL and WASO in the two groups（P〈0.01）. The patients in intervention group made significantly better outcomes than those in control group on the scores of PSAS [（15.03 ± 7.87） vs（6.72 ± 4.42）], SL [（24.73 ± 22.94） vs（19.04 ± 19.15）] and WASO [（24.07 ± 18.22） vs（17.24 ± 15.44）]（P〈0.01）. 【Conclusion】 Increasing physical exercise is effective for treating the hyperarousal of physically inactive patients with primary insomnia and is helpful to improve the sleep quality.

关 键 词：原发性失眠 体育运动 过度觉醒 咨询 

分 类 号：R74[医药卫生—神经病学与精神病学]