针刺配合中药联合治疗前部缺血性视神经病变的系统评价  

Acupuncture combined with Chinese medicine treating anterior ischemic optic neuropathy: A metaanalysis

作　　者：庞午[1] 张铭连 李亚[1] 孟兢晶 

机构地区：[1]天津中医药大学,天津300193 [2]河北省眼科医院,邢台054000

出　　处：《中国中医眼科杂志》2015年第4期241-245,共5页China Journal of Chinese Ophthalmology

基　　金：国家自然科学基金项目(81473733);河北省自然科学基金项目(H2014108029)

摘　　要：目的综合评价针刺联合中药疗法对治疗前部缺血性视神经病变的有效性。方法计算机检索Medline/Pub Med、中国生物医学文摘(CBM)、中国知网(CNKI)、中文期刊全文(VIP)及万方数字化期刊全文等数据库中建库至2014年11月以前,公开发表的针刺配合中药联合治疗前部缺血性视神经病变的随机对试验。应用Rev Man 5.2.7软件进行循证医学评价。结果符合纳入标准的文献9篇,共796只眼,针刺联合中药疗法优于单纯常规药物治疗,差异有统计学意义:总有效率比值比(OR)=3.50,95%可信区间(CI)2.41~5.09;视野缺损范围均数差(MD)=-8.33,95%CI-11.48^-5.17;平均光敏感度MD=2.07,95%CI 1.02~3.13。结论针刺联合中药治疗前部缺血性视神经病变疗效优于单纯常规药物治疗,但因本次纳入文献数量和质量存在一定局限,未来仍需多中心大样本的临床试验,以提高针药联合疗效的证据强度。OBJECTIVE To evaluate the efficacy of acupuncture combined with Chinese medicine treatment for anterior ischemic optic neuropathy （AION）. METHODS Medline, Web of Science, Chinese Biomedical Litera-ture （CBM）, China Academic Journal Network Publishing （CNKI）, China info and VIP were retrievaled on the RCTs of acupuncture combined with Chinese medicine treatment for anterior ischemic optic neuropathy, time limitation from database established to November, 2014, RevMan 5.2.7 was used to analysis the data. RESULTS Nine re-searches and 796 eyes were selected for the study. Analysis data showed an overall OR comparing the acupuncture combined with Chinese medicine to control condition was 3.50, 95%CI：2.41~5.09;Visual field defects：MD=-8.33, 95%CI：-11.48^-5.17;Visual acuity：MD=2.07,95%CI：1.02~3.13. CONCLUSIONS Associated acupuncture and traditional Chinese medicine therapy was effective for AION. Due to limitations of the quantity and quality of includ-ed studies, this conclusion has yet to be carried out in large, multicenter study to verify.

关 键 词：针刺 中药 前部缺血性视神经病变 系统评价 

分 类 号：R774.6[医药卫生—眼科]