完全性切除手术标准对非小细胞肺癌预后的影响  

Complete resection operation standards impact on prognosis of non small cell lung cancer

作　　者：连爱民 方勇 师智勇 万强辉 

机构地区：[1]平煤神马医疗集团总医院胸心外科,河南平顶山467000

出　　处：《中华临床医师杂志（电子版）》2015年第18期21-23,共3页Chinese Journal of Clinicians(Electronic Edition)

摘　　要：目的探讨完全性切除手术标准对非小细胞肺癌预后的影响。方法回顾性分析在我院行手术治疗的382例非小细胞肺癌患者的临床资料,探讨完全性切除手术标准对非小细胞肺癌预后的影响及影响的相关性因素。结果完全性切除标准患者5年的生存率为53.28%,非完全性切除标准患者5年生存率为41.23%,两组患者对比差异有统计学意义(χ2=5.129,P=0.000);单因素分析结果显示,TNM分期病理类型、手术切缘、手术范围、淋巴清扫个数、淋巴清扫组数、完全性切除标准与患者5年生存率有关(P<0.05);经多因素分析结果显示,TNM分期及完全性切除标准是患者生存率的独立影响因素(P<0.05)。结论符合完全性切除标准手术治疗非小细胞肺癌,能明显改善患者的生存率;TNM分期及完全性切除标准是影响非小细胞肺癌患者生存率的独立影响因素。Objective To investigate the effect of complete resection operation standard on the prognosis of non small cell lung cancer. Methods Retrospectively analyzed the clinical data of surgical treatment in our hospital 382 cases of patients with non small cell lung cancer, to study the factors influencing the complete resection operation standard on prognosis of non small cell lung cancer and the effect. Results The survival rate of patients with resection of safety standard of 5 years were 53.28%, non safety resection patients 5 years survival rate was 41.23%, the difference had statistical significance between two groups （23=5.129, P=0.000）; single factor analysis showed that the TNM staging and pathological types, surgical margin, the extent of surgery, lymph node dissection number, lymph node dissection group number, safety standard and resection of patients 5 years survival rate （P〈0.05） were the factors; multivariate analysis showed that TNM stage and safety standard were the independent influencing （P〈0.05）. Conclusion Meet the standard completely in resection operation for treatment of non small cell lung cancer, can significantly improve the survival rate of patients with TNM stage and resection; TNM stage and complete resection standard can influence the survival rate of patients with small cell lung cancer.

关 键 词：癌 非小细胞肺 完全性切除手术标准 相关性 

分 类 号：R734.2[医药卫生—肿瘤]