重症急性胰腺炎治疗中早期肠内营养和肠外营养的疗效对比研究  

Comparative study of the efficacy of enteral nutrition and parenteral nutrition in the treatment of severe acute pancreatitis

作　　者：郭少勇[1] 赵伟[2] 

机构地区：[1]盐城市阜宁县人民医院消化内科 [2]中国人民解放军93169部队医院

出　　处：《牡丹江医学院学报》2015年第5期21-23,共3页Journal of Mudanjiang Medical University

摘　　要：目的比较重症急性胰腺炎治疗中早期肠内营养和肠外营养的疗效。方法 56例重症急性胰腺炎患者随机分为两组,对照组予肠外营养治疗,观察组予早期肠内营养治疗,比较两组患者临床症状、炎症、营养及预后指标的差异。结果治疗后观察组血清CRP及APACHEⅡ评分低于对照组,白蛋白高于对照组,差异均有统计学意义(P<0.05);观察组患者腹痛腹胀缓解时间、血淀粉酶恢复时间及住院时间均明显短于对照组,且观察组胰腺感染发生率明显低于对照组,差异均有统计学意义(P<0.05)。结论重症急性胰腺炎治疗中采用早期肠内营养治疗可降低炎症反应程度,改善营养状态,促进临床症状的缓解,减少感染并发症的发生,对疾病的恢复有利。Objective To compare the efficacy of enteral nutrition and parenteral nutrition in the treatment of severe acute pancreatitis. Methods 56 patients with severe acute pancreatitis were randomly divided into control group and observation group. The control group received parenteral nutrition treatment,and the observation group were given early enteral nutrition therapy. The clinical symptoms,inflammation,nutrition and prognostic indicator in two groups were compared. Results After treatment,the serum CRP and APACHEⅡ scores in observation group was lower than those in control group,and albumin was also higher than that in control group,the differences were of statistically significant（ P〈0. 05）; the abdominal bloating relief time,blood amylase recovery time and hospital stay in observation group were significantly shorter than those in control group,and the incidence of pancreatic infection in observation group was significantly lower than that in control group,the difference were of statistically significant（ P〈0. 05）. Conclusion The early enteral nutrition therapy in treatment of severe acute pancreatitis can reduce the degree of inflammation,improve nutritional status,promote remission of clinical symptoms,reduce the incidence of infectious complications,and is good for the recovery of the disease.

关 键 词：重症急性胰腺炎 肠内营养 炎症反应 

分 类 号：R576[医药卫生—消化系统]