血清C反应蛋白、同型半胱氨酸与急性脑梗死的相关性分析  

The clinical significance of testing plasma hs-CRP and Hcy of acute cerebral infarction patients

作　　者：肖卫军[1] 李晓军[2] 郝洁[3] 孟燕[4] 高新明[1] 张敬[3] 冯玉明[5] 周静[5] 

机构地区：[1]新疆生产建设兵团第九师医院重症医学科,新疆额敏834601 [2]石河子大学医学院第一附属医院神经内科,新疆石河子832008 [3]新疆生产建设兵团第九师医院医教科,新疆额敏834601 [4]新疆生产建设兵团第九师医院内三科,新疆额敏834601 [5]新疆生产建设兵团第九师医院检验科,新疆额敏834601

出　　处：《农垦医学》2015年第2期160-163,共4页Journal of Nongken Medicine

摘　　要：目的:探讨血清C反应蛋白(hs-CRP)、血浆同型半胱氨酸(Hcy)水平在急性脑梗死患者中的意义。方法:检测150名(发病在72小时之内)急性脑梗死患者,150名健康体检者血清超敏C反应蛋白、同型半胱氨酸的浓度,比较病例组与对照组间浓度的差异,进一步比较病例组中神经功能缺损、吸烟两项指标的差异。结果:急性脑梗死患者血清CRP、Hcy水平均高于对照组,差异有统计学意义(=0.001);急性脑梗死患者中,神经功能缺损程度重的患者血清CRP、Hcy水平高于神经功能缺损程度轻的患者,两者之间差异有统计学意义(<0.05);吸烟患者的CRP、Hcy水平均明显高于不吸烟患者。结论:CRP、Hcy的水平均与急性脑梗死密切相关,且与神经功能缺损程度密切相关,可作为急性脑梗死的预防及脑梗死患者病情监测的重评判指标。Objective： To study the clinical significance testing plasma hs-CRP and Hcy of acute cerebral infarction patients.Methods： Plasma hs-CRP and Hcy of 150 acute cerebral infarction patients（onset in 72hours）and 150 healthy controls are tested. The hs-CRP and Hcy level were compared between the recruited healthy person group and patient group, and the further analysis about nervous dysfunction and smoking factors were done for the later.Result：Plasma hs-CRP and Hcy of acute cerebral infarction patients are significantly higher than that of the control group（P=0.001）.In acute cerebral infarction patients the moderate and severe dysfunction patients have a significant higher hs-CRP and Hcy level than that of the mild patients;（P〈0.05）.The smoker patients have a significant higher hs-CRP and Hcy level than that of the patients don＇t smoke.Conclusion： Plasma hs-CRP and Hcy has a close relationship with actue cerebral infarction and the severity of dysfunction,that maybe become the prevention and evaluation indicators in acute cerebral infarction patients.

关 键 词：高敏C反应蛋白 同型半胱氨酸 急性脑梗死 

分 类 号：R743.3[医药卫生—神经病学与精神病学]