AFP阳性胃肝样腺癌15例临床分析  

Clinical analysis of 15 cases of AFP positive hepatoid adenocarcinoma of the stomach

作　　者：邵国益[1] 张献[1] 胡根[1] 戴丽强 

机构地区：[1]江阴市人民医院腔镜外科,江苏江阴214400

出　　处：《现代肿瘤医学》2015年第21期3154-3157,共4页Journal of Modern Oncology

摘　　要：目的：探讨胃肝样腺癌患者的治疗以及预后，同时分析血清甲胎蛋白在诊断胃肝样腺癌及判断预后中的临床意义。方法：分析15例手术病理证实为胃肝样腺癌患者的临床资料。结果：15例患者，生存时间3．1～24个月，平均10．52个月，术前血清AFP浓度范围为25．23～13500μg／L。结论：胃肝样腺癌AFP水平波动范围大，血清AFP升高是胃肝样腺癌重要的临床病理特点，在胃肝样腺癌诊治中具有重要价值，可作为早期诊断的条件之一，同时可以用于监测肿瘤复发与转移。胃肝样腺癌预后极差，合并肝转移或者门静脉癌栓患者建议避免手术治疗。Objective：To investigate the treatment and prognosis of the hepatoid adenocarcinoma of the stomach （HAS） ,and analyze serum alpha fetoprotein （AFP） clinical significance of HAS in diagnosis and prognosis. Meth- ods：Collected 15 cases of pathologically confirmed HAS with positive AFP. Results：The survival time of all 15 pa- tients was 3. 1 -24 months, the average was 10.52 months. Serum AFP concentrations ranged from 25.23 to 13 500μLg/L. Conclusion：AFP level of HAS fluctuate widely. And elevate AFP is an important clinical and pathologi- cal feature of HAS. It is very useful for the diagnosis and treatment of HAS. Its useful for the early diagnosis and moni- tor of recurrence and metastasis of tumor. The prognosis of HAS is very poor, especially for patients with liver metasta- sis or portal vein tumor thrombus. We should avoid operations for metastasis cases.

关 键 词：胃肝样腺癌 血清AFP 临床分析 

分 类 号：R735.2[医药卫生—肿瘤]