SOX9与NM23基因在前列腺癌中的表达  

Expression of SOX9 and NM23 Gene in Prostate Cancer

作　　者：任彩虹[1] 

机构地区：[1]福建省福州市福建医科大学附属第一医院病理科,350005

出　　处：《中国继续医学教育》2015年第28期42-43,共2页China Continuing Medical Education

摘　　要：目的探讨SOX9、NM23基因在前列腺癌中的表达。方法选取16例前列腺癌患者与24例前列腺良性增生患者,取其病理组织采用实时荧光定量PCR测定其mRNA表达量。结果前列腺癌组患者NM23、SOX9 mRNA表达量与前列腺增生组患者比较明显更高,差异均有统计学意义(P<0.05)。结论通过对NM23、SOX9 mRNA表达量进行测定可为前列腺癌临床诊断提供可靠依据。Objective To investigate the expression of SOX9 and NM23 gene in prostate cancer.Methods 16 patients with prostate cancer and 24 patients with benign prostatic hyperplasia,take the pathological tissue,the expression of mRNA was measured by real-time fluorescence quantitative PCR.Results The expression of SOX9 and mRNA NM23 in prostate cancer group was significantly higher compared with that in patients with benign prostatic hyperplasia（P〈0.05）.Conclusion The expression of SOX9 and mRNA NM23 can be measured,and it can provide reliable basis for clinical diagnosis of prostate cancer.

关 键 词：前列腺癌 NM23基因 SOX9基因 表达 

分 类 号：R737.25[医药卫生—肿瘤]