四肢远端穴位对急性缺氧志愿者心功能调节规律研究  

Effect of Electroacupuncture Stimulation of Acupoints at the Distal Limbs on Heart Function of Volunteers with Acute Hypoxia

作　　者：董亚琴[1] 修春英[1] 萨喆燕[1] 许金森[1] 

机构地区：[1]福建省中医药研究院,福州350003

出　　处：《针刺研究》2015年第5期402-408,共7页Acupuncture Research

基　　金：国家自然科学基金青年项目(No.81403490);福建省科技厅省属公益类项目(No.2014R1035-6);福建省教育厅中青年教师教育科研B类项目(No.JB 14050);福建省科技厅自主选题项目(No.2013fjzyyk-1);福建省卫生厅青年基金(No.2013-1-42)

摘　　要：目的:观察针刺四肢远端穴位对健康志愿者急性缺氧时心功能的调节规律。方法:20名健康志愿者,采用同体对照方法,分为对照组、曲泽组、手三里组、足三里组、光明组。在吸入低氧混合气体条件下,电针曲泽、手三里、光明、足三里各20min,采用血液动力学监护仪记录心输出量(CO)、心率(HR)、左心做功(LCW)、左心室射血时间(LVET)在针刺前后的变化。结果:电针曲泽、足三里穴能显著降低急性缺氧所致的CO、LCW、HR升高(P<0.05),显著延长LVET(P<0.05);电针手三里、光明穴无上述作用。结论:四肢远端穴位的功能主治与神经节段支配无明确关联,与所属经络的循行路径密切相关。Objective To observe the effect of electroacupuncture（EA）stimulation of different acupoints at the distal ends of the limbs on cardiac function in volunteers with acute hypoxia,so as to determine if its actions are realized by way of segmental innervations or meridians.Methods Twenty healthy volunteers were divided into control,Quze（PC 3）,Shousanli（LI 10）,Guangming（GB 37）and Zusanli（ST 36）groups（both PC 3and LI 10 are innervated by spinal C3-C6,and both ST 36 and GB 37 innervated by L5-S1）.Acute hyoxia（simulating the conditions of about 5 000 mheight above the sea level）was induced by asking the volunteers to inhale low-oxygen gas mixture（10.8% O2＋ 89.2% N2）for 30 min,when,the participants＇ cardiac output（CO）,heart rate（HR）,left cardiac work（LCW）,left ventricular ejection time（LVET）were measured using a ICG Monitor and EA stimulation（10Hz/20 Hz,1-2V）was also conducted for 20 min following inhaling low-oxygen for 10 min.Results Before low-oxygen inhale,the levels of CO,HR,LCW and LVET ratios（test value/basic value）of the control,PC 3,LI 10,ST 36 and GB 37 groups were comparable（P〉0.05）.After inhaling low-oxygen gas mixture for 10 min,the levels of CO,HR,and LCW ratios were significantly increased,and the LVET ratios were notably decreased in the five groups（P〈0.05）.Compared with the 10min-low-oxygen inhale of the same one group,CO and HR ratios at both EA 10 min and 20 min in the PC 3and ST 36 groups,LCW ratios at EA 10 min in both PC 3and ST 36 groups were notably down-regulated（P〉0.05）,while the LVET ratios of both PC 3and ST 36 groups was significantly prolonged（P〈0.05）.No significant changes of CO,HR,LCW and LVET ratios were found in the LI 10 and GB 37 groups after EA for 10 min and 20min（P〈0.05）.Conclusion EA stimulation of Quze（PC 3）and Zusanli（ST 36）,but not Shousanli（LI 10）and Guangming（GB 37）can lower CO,HR and LCW levels and increase LVET in volunteer subjects undergoing acute hypoxia,suggesting tha

关 键 词：急性缺氧 电针 左心功能 四肢远端穴位 神经节段 经络 

分 类 号：R224.2[医药卫生—中医基础理论]