颜色定量分析在色素内镜诊断早期食道癌中的应用  

Quantitative analysis of color application in early carcinoma of esophagus in the pigment endoscope diagnosis

作　　者：李腾飞[1] 刘鹏飞[1] 叶武[1] 陆小峰[1] 钱建忠[1] 

机构地区：[1]东南大学附属江阴医院,214400

出　　处：《今日健康》2015年第9期317-318,共2页

摘　　要：目的：探析色素内镜在上消化道早期癌及癌前病变的诊断价值。方法：随机选取2010年1月~2013年1月在我院住院就诊的88例可能出现消化道早期癌病变的患者作为研究对象，对其内镜下利用Lugole液对患者的食管Lugole液黏膜进行染色，将染色之前和染色之后的内镜诊断结果进行对比，并与病理活检结果进行比较。结果：在88例患者中，发现的异常染色灶共95个，其中高级别上皮内瘤变有15个（15．79％），低级别上皮内瘤变有18个（18．95％），鳞状细胞癌有30个（31．58％），黏膜组织慢性炎症有32个（33．68％）。在这四组不同的病理变化中，染色后颜色分量R／R）（红色）及H／Ht（色调）的参数与组间参数对比差异明显，具有统计学意义（P〈0．05）。结论：色素内镜应用于消化道早期癌及癌前病变的诊断，可以有效提高诊断率，且诊断方法既简便又安全，值得临床广泛推广应用。Objective： analysis of the pigment endoscope indiagnosis of early upper gastrointestinal cancer and precancerous lesions. Method： randomly selected in 2010January ~2013 year in January in our hospital 88 cases ofpossible treatment of lesions in digestive tract early cancerpatients as the research Object, on the use of Lugolesolution on the esophageal mucosa of patients with Lugolesolution were stained the endoscopic, endoscopic diagnosis before and after the dyeing dyeing results were compared, and compared with the results of pathological biopsy. Results： in 88 patients, abnormal staining focifound a total of 95, ,including high grade intraepithefial neoplasia 15 （15.79%）, low grade intraepithelial neoplasia18 （18.95%）, squarnous cell carcinoma in 30 （31.58%）,mucosa of chronic inflammation with 32 （33.68%）. In the four groups of different pathological changes, dyed the color components R/R＇ （red） and H/H＇ （hue） parameters difference contrast parameters and inter group obviously,with statistical significance （P 〈 0.05）. Conchision：chromoendoscopy used in early diagnosis of digestive tractcancer and precancerous lesions, can effectively improve the rate of diagnosis, and the diagnostic method is a simple and safe, is worthy of extensive promotionapplication.

关 键 词：色素内镜 上消化道早期癌 癌前病变 诊断价值 

分 类 号：R735.1[医药卫生—肿瘤]