原发性输尿管癌患者手术预后因素分析  

Prognostic factors for surgical outcomes of primary ureteral carcinoma

作　　者：许盛飞[1] 杜广辉[1] 陆金金[1] 刘继红[1] 王少刚[1] 陈志强[1] 庄乾元[1] 宋晓东[1] 陈忠[1] 胡志全[1] 叶章群[1] 杨为民[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院泌尿外科

出　　处：《临床外科杂志》2015年第10期783-785,共3页Journal of Clinical Surgery

摘　　要：目的探讨影响原发性输尿管癌患者生存的预后因素。方法回顾性分析48例原发性输尿管癌患者资料，采用Kaplan．Meier法和Cox回归法分析各因素对预后的影响。结果患者平均随访31个月（3～129个月），48例患者中，18例死亡，患者1年生存率为77．0％，3年生存率为64．9％，5年生存率为54．1％。单因素分析结果显示：年龄、性别、临床分期、肿瘤位置、腰痛、肉眼血尿、中性粒细胞与淋巴细胞比值（NLR）与原发性输尿管癌患者的预后有关（P〈0．05）。Cox多因素分析结果显示：临床分期、年龄、NLR是影响原发性输尿管癌患者预后的独立预后因素（P〈0．05）。结论在原发性输尿管癌患者中，临床分期越高、年龄越大、NLR越大，患者的预后越差。Objective To analyze the prognostic factors for patients with primary ureteral carcinoma. Method The clinical data of 48 patients with primary ureteral carcinoma were analyzed retrospectively. The effects of relative factors on prognosis were analyzed by Kaplan-Meier analysis and Cox regression. Result The mean follow-up period was 31 months （range ,3-129 months ）. Eighteen patients died. The 1-, 3-, and 5 - year survival rates were 77.0% , 64.9 % , and 54.1% , respectively. Univariate analysis showed that age, gender, clinical stage, tumor location, backache, gross hematuria, and neutrophil-lympho- cyte ratio（NLR） were related to the prognosis （ P 〈 0.05 ）. Cox muhivariate analysis demonstrated that clinical stage, age, and NLR were independent risk factors for the prognosis （ P 〈 0.05 ）. Conclusion For primary ureteral carcinoma patients,increased age, advanced tumor stage and large NLR were all associated with poor survival outcomes.

关 键 词：原发性输尿管癌 预后 多因素分析 

分 类 号：R737.13[医药卫生—肿瘤]