精浆脂蛋白(a)、锌和前列腺特异性抗原含量与精液液化的关系  

Relationship of levels of seminal plasma lipoprotein( a),Zn2 +and prostate specific antigen in the semen with abnormal semen liquefaction

作　　者：张健清[1] 王东[1] 黄楚梅[1] 张式鸿[1] 蔡丹[1] 

机构地区：[1]中山大学附属第一医院检验医学部,广州510080

出　　处：《中国性科学》2015年第10期92-94,共3页Chinese Journal of Human Sexuality

摘　　要：目的:探讨精浆脂蛋白(a)、锌和前列腺特异性抗原(PSA)与精液液化的关系。方法:筛选精液液化异常患者和精液液化正常男性各200例,显色法测定精浆锌离子(Zn2+),酶联免疫法测定PSA,乳胶增强免疫透射比浊法测定脂蛋白(a),对比分析两组测定结果。结果:异常组精浆Zn2+平均含量为(90.0±35.1)μg/m L,脂蛋白(a)水平为(550±250)μg/m L;正常组精浆Zn2+平均含量为(125.1±25.5)μg/m L,脂蛋白(a)水平为(301±98)μg/m L,两者差异有统计学意义(均P<0.01)。异常组精浆PSA含量为(0.81±0.21)mg/m L,正常组精浆PSA含量为(1.31±0.30)mg/m L,两者差异有统计学意义(P<0.05)。结论:精液液化异常可能与精浆脂蛋白(a)水平增高,Zn2+及PSA含量偏低有一定的相关性。Objectives： To explore the relationship of levels of seminal plasma lipoprotein（ a）,Zn2 ＋ and prostate specific antigen in the semen with abnormal semen liquefaction. Methods： 200 patients with abnormal semen liquefaction and 200 men with semen liquefaction were selected. The level of seminal zinc was detected by color- developing method. The level of PSA in seminal was measured by ELISA and the lipoprotein（ a） was measured by latex enhanced immunoturbidimetric assay. Results： The levels of Zn2 ＋in abnormal group and normal group were（ 90. 0 ± 35. 1） μg / m L and（ 125. 1 ± 25. 5） μg / m L respectively,with significant difference（ P〈0. 01）. The levels of lipoprotein（ a） in abnormal group and normal group were（ 550 ± 250） μg / m L and（ 301 ± 98） μg / m L respectively,with significant difference（ P〈0. 01）. The levels of PSA in abnormal group and normal group were（ 0. 81 ± 0. 21） mg/m L and（ 1. 31 ± 0. 30） mg/m L respectively,with significant difference（ P〈0. 05）. Conclusion： The levels of seminal lipoprotein（ a）,Zn2 ＋and PSA should be taken into account in the diagnosis of male infertility caused by abnormal liquefaction.

关 键 词：脂蛋白(a) 锌 前列腺特异性抗原 精液液化 

分 类 号：R737.25[医药卫生—肿瘤]