丹参川芎嗪注射液联合依达拉奉治疗急性脑梗死的疗效分析  

Analysis of curative effect by salviae miltiorrhizae ligustrazine injectioncombined withedaravone injection in the treatment of acute cerebral infarction

作　　者：郭宇[1] 

机构地区：[1]辽宁省精神卫生中心神经内科,112300

出　　处：《中国现代药物应用》2015年第21期20-21,共2页Chinese Journal of Modern Drug Application

摘　　要：目的探讨丹参川芎嗪注射液联合依达拉奉治疗急性脑梗死患者的疗效。方法 96例急性脑梗死患者随机分为研究组与对照组,各48例。研究组给予依达拉奉注射液联合丹参川芎嗪注射液静脉滴注,对照组给予依达拉奉注射液静脉滴注,两组其他治疗方案相同。治疗14 d后进行美国国立卫生院神经功能缺损评分(NIHSS)和疗效分析,并观察用药期间发生的不良反应。结果治疗后14 d研究组NIHSS评分明显低于对照组(P<0.05),总有效率高于对照组(P<0.05),两组均未发生严重不良反应。结论丹参川芎嗪注射液联用依达拉奉能改善急性脑梗死患者的神经功能缺损程度,提高临床疗效,且不良反应较少。Objective To investigate curative effect by salviae miltiorrhizae ligustrazine injection combined with edaravone injection in the treatment of acute cerebral infarction.Methods A total of 96 acute cerebral infarction patients were randomly divided into research group and control group, with 48 cases in each group. The research group received salviae miltiorrhizae ligustrazine injection combined with edaravone injection by intravenous drip, and the control group received edaravone injection by intravenous drip. Both groups received the same treatment measures in the other aspects. National institutes of health stroke scale （NIHSS） and curative effect analysis were made in 14 d after treatment, along with observation of adverse reactions during medicine administration.Results In 14 d after treatment, the research group had much lower NIHSS score than the control group （P〈0.05）, and its total effective rate was higher than the control group （P〈0.05）. Both groups had no severe adverse reactions.Conclusion Combination of salviae miltiorrhizae ligustrazine injection and edaravone injection can improve degree of nervous functional defects in acute cerebral infarction patients, and improve clinical effect, with few adverse reactions.

关 键 词：丹参川芎嗪注射液 依达拉奉注射液 急性脑梗死 疗效 

分 类 号：R743.33[医药卫生—神经病学与精神病学]