13例乳腺浸润性微乳头状癌临床特征分析  

Clinicopathologic features of invasive micropapillary carcinoma of the breast in 13 cases

作　　者：王梅[1] 汤鹏[2] 

机构地区：[1]中南大学湘雅医院,长沙410008 [2]海南省人民医院乳腺外科,海口570311

出　　处：《中华实用诊断与治疗杂志》2015年第11期1100-1102,共3页Journal of Chinese Practical Diagnosis and Therapy

基　　金：国家临床重点专科建设项目经费资助(卫办医政函2012649号)

摘　　要：目的探讨乳腺浸润性微乳头状癌(invasive micropapillary carcinoma,IMPC)临床病理特征。方法分析13例IMPC患者(IMPC组)临床资料,检测雌激素受体、孕激素受体、人类表皮生长因子受体-2、抗原Ki-67等水平,并与同期26例乳腺浸润性导管癌患者(对照组)进行比较。结果 IMPC组淋巴结转移率(92.31%)、pTNM分期Ⅲ期以上比率(61.54%)高于对照组(46.15%、26.92%)(P<0.05);2组雌激素受体、孕激素受体、人类表皮生长因子受体-2、抗原Ki-67阳性表达率比较差异均无统计学意义(P>0.05)。结论 IMPC具有高淋巴结转移、高侵袭性等特征。Objective To explore the clinicaopathologic features of invasive micropapillary carcinoma （IMPC） of the breast. Methods The clinicopathologic features of 13 IMPC patients were retrospectively analyzed. The levels of estrogen receptor （ER）, progesterone receptor （PR）, human epidermal growth factor receptor 2 （Her-2） and antigen Ki-67 （Ki-67） were detected and compared with 26 patients with invasive ductal carcinoma. Results The rate of lymph node metastasis and the total rate of stage III and IV were 92.31% and 61.54% in IMPC group, significantly higher than those in control group （46.15%, 26.92%） （P〈0.05）. There were no significant differences in positive expressions of ER, PR, Her-2 and Ki-67 between two groups （P〉0.05）. Conclusion The high rate of lymph node metastasis and strong invasiveness are the notable biological features of breast IMPC.

关 键 词：乳腺癌 浸润性微乳头状癌 组织病理 

分 类 号：R737.9[医药卫生—肿瘤]