色素胃镜对食管早癌及异型增生的诊断价值  

Clinical Values of Chromoendoscopy in Esophageal Lesions

作　　者：张韵婷[1] 操寄望[1] 季梦遥[1] 董卫国[1] 

机构地区：[1]武汉大学人民医院消化内科,湖北武汉430060

出　　处：《武汉大学学报（医学版）》2015年第6期918-921,共4页Medical Journal of Wuhan University

基　　金：湖北省自然科学基金资助课题(编号:2013BCB014)

摘　　要：目的:探究色素胃镜在食管早癌及异型增生诊断中的应用价值。方法:对我院170例胃镜检查发现可疑食管黏膜病变者,用2.0%卢戈氏碘液染色后取活检,结合病理分析,探讨内镜下病变部位碘染色改变与活检病理结果的关系。结果:170例患者中有139例呈现碘不染色,活检病理诊断食管癌36例,异型增生39例;碘淡染及碘不染色者仅有6例异型增生,余均为慢性炎症。内镜下碘不染区异型增生及食管癌共75例,检出率高于碘淡染及碘正常染色区(χ2=16.283,P<0.05)。结论:色素胃镜能鉴别食管黏膜病变,指导活检可提高食管早癌及异型增生的检出率。Objective：To investigate the diagnostic value of lugol chromoendoscopy for detection of early esophageal cancer and precancerous lesion.Methods：2.0% Lugol＇s solution was sprinkled to the lesions of 170 patients who received routine endoscopy showed suspicious abnormal changes,then biopsy was taken on in order to study the relationship between staining and pathological results.Results：Of 170 patients,139cases were unstaining with Lugol＇s solution,and the pathological results showed 36 cases of early esophageal cancer and 39 cases of dysplasia.There are only 6cases of dysplasia in minor staining lesions and normal staining lesions.The detection rate of dysplasia and early esophageal cancer in Lugol non-stained area was significantly higher than that in lightly stained and normal stained lesions（χ2=16.283,P〈0.05）.Conclusion：Chromoendosccopy with Lugol＇s solution can identify esophageal lesions and improve the detection rate of early esophageal cancer and dysplasia significantly.

关 键 词：色素胃镜 卢戈氏碘液 食管早癌 异型增生 

分 类 号：R571[医药卫生—消化系统]