北京社区精神分裂症患者2型糖尿病发生率及其相关因素  

A study of prevalence rate and risk factors of type Ⅱ diabetes mellitus in patients with schizophrenia in Beijing community

作　　者：闫芳[1] 任艳萍[1] 侯也之[1] 李文咏 穆莉莉 王诚 李文秀 吴晓梅[1] 陶玉芬[1] 徐会利[2] 朱玉玲 苏京利 陈国澜 陈玲 

机构地区：[1]首都医科大学附属北京安定医院精神疾病诊断与治疗北京市重点实验室,北京市100088 [2]北京市朝阳区第三医院 [3]北京昌平区精神卫生防治院 [4]北京海淀区精神卫生防治院

出　　处：《精神医学杂志》2015年第5期321-325,共5页Journal of Psychiatry

基　　金：首都医学发展科研基金(编号:2005-1001);北京市卫生局;北京市中医管理局青年科学研究资助项目(编号:QN2008-003)

摘　　要：目的：了解北京社区精神分裂症患者发生2型糖尿病的比例及其人口学特点。方法以北京市4个区县540名18～65岁慢性精神分裂症患者作为调查对象。使用一般人口学特征、疾病特征、用药情况、糖尿病病史登记表等进行访谈，检测身高、体质量及空腹血糖。结果精神分裂症患者糖尿病的发生率为15．7％，有随着年龄的增长而增加的趋势（P＜0．05）；单因素分析显示精神分裂症糖尿病患者与非糖尿病患者在发病次数、发病年龄、总病程方面比较差异有统计学意义（P＜0．05）。 Logistic回归分析显示控制其他影响因素的情况下，糖尿病的发生与急性起病、病程长、发病年龄晚有关（ P＜0．05）。结论慢性精神分裂症患者中糖尿病的发生率高于正常人群，与发病形式、发病年龄和病程有关。Objective To explore the prevalence rate and demographic characteristics of type II diabetes mellitus in patients with schizophrenia in Beijing community.Methods A total of 540 patients with chronic schizophrenia from 18 to 65 years old in four districts and counties of Beijing were selected and investigated with basic socio-demographic, disease attribute,medication, history of diabetes, height, weight and fasting blood glucose.Results The prevalence rate of diabetes mellitus in patients with schizophrenia was 15.7% which was positively related with the age of patients （ P 〈0.05）.Univariate analysis showed significant differences for recurrence times, age of onset and course of disease between the schizophsenia patients with diabetes mellitus and the schizophrenia patients without diabetes mellitus （P〈0.05）.Logistic regression analysis showed the onset of diabetes mellitus in the patients was related to acute onset, long course of disease and late age of onset （P〈0.05）.Conclusion It’s serious for the prevalence rate of diabetes mellitus in patients with schizophrenia which is related to the form and age of onset as well as course of disease.

关 键 词：精神分裂症 糖尿病 发生率 

分 类 号：R749.3[医药卫生—神经病学与精神病学]