超声造影诊断胰腺囊性病变与MRI及病理的对照研究  

Application of contrast enhanced ultrasound in the diagnosis of pancreatic cystic lesions：comparison with MRI and pathology

作　　者：范智慧[1] 严昆[1] 王延杰[1] 杨薇[1] 吴薇[1] 陈敏华[1] 

机构地区：[1]北京大学肿瘤医院暨北京市肿瘤防治研究所超声科恶性肿瘤发病机制及转化研究教育部重点实验室,100142

出　　处：《中华超声影像学杂志》2015年第10期855-859,共5页Chinese Journal of Ultrasonography

基　　金：基金项目：首都临床特色应用研究（Z131107002213147）

摘　　要：目的应用常规超声、超声造影（contrastenhancedultrasound，CEUS）及增强MRI对胰腺囊性病变进行诊断，探讨CEUS在胰腺囊性病变中的应用价值。方法32例经手术或穿刺病理证实的胰腺囊性病变患者，分别应用常规超声、CEUS及增强MRI对胰腺囊性病变进行诊断，并以病理结果为金标准，比较不同影像方法的诊断能力。结果32例胰腺囊性病变包括浆液性囊腺瘤8例，黏液性囊腺类肿瘤6例，导管内乳头状黏液瘤3例，实性假乳头状瘤4例，神经内分泌肿瘤3例，胰腺癌6例，潴留囊肿1例，炎症性肌纤维母细胞肿瘤伴囊性变1例。常规超声诊断准确率46．88％（15／32），CEUS诊断准确率75．00％（24／32），增强MRI为78．13%（25／32）。CEUS、增强MRI的诊断准确率差异无统计学意义（P=0．768）；CEUS、增强MRI的诊断准确率均明显高于常规超声，差异有统计学意义（P〈0．05）。结论CEUS对胰腺囊性病变的诊断准确率优于常规超声，与增强MRI接近。Objective To explore the diagnostic value of contrast enhanced ultrasound （CEUS） by comparison with enhanced MRL Methods Thirty-two cases with pancreatic cystic lesions confirmed by surgery or biopsy were enrolled. Ultrasound,CEUS and MRI were applied respectively for the diagnosis of 32 cases. The diagnostic ability of different imaging methods were compared according to pathological results as the gold standard. Results The 32 cases include 8 cases of serous cystadenoma, 6 cases of mucinous cystic neoplasm, 3 cases of intraductal papillary mucinous neoplasm, 4 cases of solid pseudopapillary tumor,3 cases of neuroendocrine tumor,6 cases of pancreatic carcinoma, 1 case of cyst and 1 case of inflammatory myofibroblastic tumor. The diagnostic accuracies of ultrasound,CEUS and MRI were 46.88% （15/32）,75.00% （24/32） and 78.13% （25/32） respectively. There was no significant difference between the diagnostic accuracies of CEUS and MRI （ P = 0.768）. The diagnostic accuracies of CEUS and MRI were higher than that of ultrasound （ P 〈0.05）. Conclusions CEUS has obvious superiority over ultrasound in the diagnostic accuracy of pancreatic cystic lesions. The diagnostic ability of CEUS is similar to that of MRI.

关 键 词：超声检查 微气泡 胰腺疾病 囊性病变 磁共振成像 

分 类 号：R735.9[医药卫生—肿瘤]