不同直径卵泡排卵对自然周期冻融胚胎移植临床结局的影响  

Influence of different size follicle ovulation on clinical outcomes in women undergone frozen-thawed embryo transfer

作　　者：李玉梅[1] 李欣凝[1] 刘冬娥[1] 

机构地区：[1]中南大学湘雅医院生殖医学中心,长沙410008

出　　处：《生殖医学杂志》2015年第11期902-905,共4页Journal of Reproductive Medicine

摘　　要：目的了解不同直径卵泡排卵对自然周期冻胚移植患者临床妊娠结局的影响。方法回顾性分析2011年1月至2013年12月自然周期冻融胚胎移植的427个周期。其中135个周期小卵泡排卵后行冻融胚胎移植,为研究组;对照组为292个周期正常大小卵泡排卵后行冻融胚胎移植的患者。观察指标为种植率、临床妊娠率、流产率、异位妊娠率及活产率。结果小卵泡排卵组与对照组的种植率(29.9%vs.29.6%,P=0.91)、临床妊娠率(44.4%vs.47.2%,P=0.78)、流产率(13.3%vs.12.3%,P=0.67)、异位妊娠率(5.0%vs.2.9%,P=0.72)及活产率(36.3%vs.40.1%,P=1.00)比较,均无统计学差异(P>0.05)。结论在行自然周期冻融胚胎移植时,与正常大小卵泡排卵组比较,小卵泡排卵组可获得相似的临床妊娠结局。Objective： To evaluate the influence of different size follicle ovulation on the pregnancy outcomes of frozen-thawed embryo transfer performed in natural cycles（FET-NC）. Methods： The data of 427 FET-NC treatment cycles carried out between January 2011 and December 2013 were retrospectively analyzed. Among them, 135 cycles were performed FET-NC after small size follicle ovulation as study group,and 292 cycle were performed FET-NC after normal size follicle ovulation as control group. miscarriage, eetoplc The observation parameters included the rates of implantation, clinical pregnancy, pregnancy and live birth. Results： No significant differences were found in implantation rate（29.9% vs. 29.6%, P= 0.91）, clinical pregnancy rate（44.4% vs. 47.2%,P=0.78）,miscarriage rate（13.3% vs. 12.3%,P=0.67）, ectopic pregnancy rate （5.0% vs. 2.9%, P = 0.72） and live-birth rate （36.3% vs. 40.1%, P = 1.00） between the two groups（P〉0.05）. Conclusions： The clinical outcomes of FET-NC have not been influenced by the size of dominant follicle,and treatment should not be canceled only because of small follicular ovulation.

关 键 词：小卵泡排卵 自然周期 冻胚移植 

分 类 号：R[医药卫生]