Irvine-Gass综合征中医体质等相关因素的系列调查研究  

Investigation on constitution of TCM and factors associated with Irvine-Gass syndrome

作　　者：曾东兴[1] 秦伟[1] 张月[1] 刘丹[1] 李懿[1] 陈一兵[1] 王雪菁[1] 翟楠[1] 王炜[1] 刘春兰[1] 

机构地区：[1]广州中医药大学附属中山医院,中山528400

出　　处：《中国中医眼科杂志》2015年第5期323-326,共4页China Journal of Chinese Ophthalmology

基　　金：广东省中山市科技局(20132A185);广东省中山市科技局(20102A091)

摘　　要：目的初步调查不同体质类型的白内障患者行超声乳化白内障吸除术,术后黄斑囊样水肿发病率的差异性及其影响发病的相关因素。方法收集调查387例387只眼行超声乳化白内障吸除术的患者。参照中华中医药学会颁布实施的中医体质分类与判定标准,依据《中医体质分类与判定表》进行问卷调查。观察术眼术前术后黄斑部光学相干断层扫描的变化等相关数据。结果 (1)体质:387例调查对象,平均年龄为67岁。平和体质207例,阳虚体质57例,气虚体质51例,其他体质总共72例。(2)黄斑囊样水肿:黄斑囊样水肿者共9例,发病率为2.32%,其中气虚体质占6例,发病率为11.76%;平和体质占3例,发病率为1.44%。气虚型体质黄斑囊样水肿的发病率,经c2检验,P<0.05,差异具有统计学意义。(3)阳虚型体质与气虚型体质患者术前及术后视网膜神经上皮层厚度变化,经t检验,P<0.05,差异具有统计学意义。(4)性别及血型与黄斑囊样水肿:男性及女性患者黄斑囊样水肿发病率,经c2检验,P>0.05,差异无统计学意义。4种血型患者黄斑囊样水肿的发病率,经c2检验,P>0.05,差异无统计学意义。(5)血糖与视网膜神经上皮层厚度的关系:血糖值与术前及术后视网膜神经上皮层厚度经相关系数的假设检验,相关系数分别为(r)=0.016,P>0.05、(r)=0.012,P>0.05,差异无统计学意义。结论 (1)本研究的白内障患者中平和体质居多,其次为阳虚体质,再次为气虚体质。(2)气虚体质患者较其他各型体质患者,白内障超声乳化术后1周,黄斑囊样水肿的发病率更高,具有倾向性、易感性。(3)白内障超声乳化术后1周,阳虚型体质与气虚型体质患者视网膜神经上皮层厚度会发生变化。且该两种体质患者视网膜神经上皮层术后平均厚度均较术前平均厚度增加。(4)黄斑囊样水肿的发病率与性别及血型无关。(5)血糖值与视网膜神经上皮层厚度尚不能认为�OBJECTIVE To investigate the prevalence rate of cystoid macular edema difference after pha- coemulsification surgery on cataract patients of different kinds of constitution of TCM. METHODS There were 387 cases of cataract patients after phacoemulsification surgery. Referencing to the Category and Judgment Standard of Constitution of TCM, promulgated by China Association of Chinese Medicine, questionnaire survey was done accord- ing to the Category and Judgment of Constitution of TCM Table. Observed the macular changes by optical coherence tomography before and after surgery. RESULTS ①Constitution of TCM： 387 cases of cataract patient＇s mean age was 67. There were 207 cases of Pinghe Constitution, 57 cases of Yang Deficiency Constitution, 51cases of Qi Defi- ciency Constitution, and 72 cases of other kinds of Constitution. ②Cystoid macular edema： there were 9 cases of cys- toid maeular edema, which Qi Deficiency Constitution accounting for 6 eases, while Pinghe Constitution accounting for 3 case. The study showed that the prevalence rate of cystoid macular edema was 2.32% in population. The preva- lence rate of cystoid macular edema of Qi Deficiency Constitution group was 11.76%, while Pinghe Constitution group was 1.44%. The prevalence rate of cystoid macular edema was significantly different between Qi Deficiency Constitution group and population （chi-square test, P〈0.05）.③The retinal nerve fiber layer＇s thickness changes of Yang Deficiency Constitution group and Qi Deficiency Constitution group were significantly different between before surgery and after surgery （t test, P〈0.05）. @Gender and Blood Type： The prevalence rate of cystoid macular edema was not significantly different between male group and female group （chi-square test, P〉0.05）. The prevalence rate of cystoid macular edema was not significantly different between four blood type groups （chi-square test, P〉O.05）. ④Glucose and the retinal nerve fiber layer＇s thickness： Correlation between the glucose and t

关 键 词：超声乳化 白内障 Irvine-Gass综合征 中医体质 光学相干断层成像术 黄斑水肿 

分 类 号：R776[医药卫生—眼科] R774.5[医药卫生—临床医学]